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ZKSCAN1 Knockout Cell Lines

Gene: ZKSCAN1

Official Full Name: zinc finger with KRAB and SCAN domains 1provided by HGNC

Gene Summary: This gene encodes a member of the Kruppel C2H2-type zinc-finger family of proteins. This encoded protein may function as a transcription factor that regulates the expression of GABA type-A receptors in the brain. Transcripts from this gene have been shown to form stable and abundant circular RNAs. Elevated expression of this gene has been observed in gastric cancer and the encoded protein may stimulate migration and invasion of human gastric cancer cells. [provided by RefSeq, Oct 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34711 ZKSCAN1 Knockout cell line (HeLa) Human ZKSCAN1 1:3~1:6 Negative Online Inquiry
KO34712 ZKSCAN1 Knockout cell line (HCT 116) Human ZKSCAN1 1:2~1:4 Negative Online Inquiry
KO34713 ZKSCAN1 Knockout cell line (HEK293) Human ZKSCAN1 1:3~1:6 Negative Online Inquiry
KO34714 ZKSCAN1 Knockout cell line (A549) Human ZKSCAN1 1:3~1:4 Negative Online Inquiry

Background

ZKSCAN1 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZKSCAN1 gene has been effectively disrupted. The ZKSCAN1 gene encodes a zinc finger transcription factor known to play a critical role in regulating gene expression, particularly involved in various cellular processes such as cell proliferation, differentiation, and apoptosis. By employing techniques such as CRISPR-Cas9 or homologous recombination, these knockout cell lines provide researchers with an invaluable tool to elucidate the gene's functional role in biological pathways and its implications in disease.

The primary function of the ZKSCAN1 gene is to modulate transcriptional networks that govern cellular responses to physiological and pathological conditions. By studying ZKSCAN1 knockout cell lines, scientists can investigate the resulting phenotypic changes, allowing for a deeper understanding of its role in cancer biology, metabolic disorders, and developmental processes. Moreover, the disruption of ZKSCAN1 provides a unique opportunity to explore compensatory pathways and potential therapeutic targets, particularly in conditions where ZKSCAN1 expression is dysregulated.

In terms of scientific significance, ZKSCAN1 knockout cell lines are particularly relevant in cancer research, as the gene has been implicated in tumor initiation and progression. These cell lines enable researchers to conduct high-throughput screening of drug candidates that may specifically target pathways influenced by ZKSCAN1. This capability is critical for advancing personalized medicine approaches, as understanding both the oncogenic and tumor-suppressive functions of this gene could lead to novel therapeutic strategies.

The unique selling proposition of our ZKSCAN1 Gene Knockout Cell Lines lies in their validated performance and reproducibility. Each cell line is rigorously characterized to ensure stable knockout efficiency and consistency across experiments, making them superior to competitors that may offer less rigorously validated options. Our product is designed with researchers’ needs in mind, providing a reliable model that enhances reproducibility and accelerates discovery.

For researchers and clinicians alike, the availability of ZKSCAN1 knockout cell lines represents a significant advancement in functional genomics and translational research. These tools not only facilitate a better understanding of gene function but also assist in the development of innovative therapeutic approaches.

Our company specializes in the production of high-quality, genetically modified cell lines, backed by a team of experienced scientists committed to supporting the research community. We pride ourselves on our expertise in genetic engineering techniques, ensuring that our products not only meet but exceed the expectations of researchers aiming to push the boundaries of scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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