Gene: ZBTB14
Official Full Name: zinc finger and BTB domain containing 14provided by HGNC
Gene Summary: Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in negative regulation of DNA-templated transcription. Located in aggresome; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34785 | ZBTB14 Knockout cell line (HeLa) | Human | ZBTB14 | 1:3~1:6 | Negative | Online Inquiry |
KO34786 | ZBTB14 Knockout cell line (HCT 116) | Human | ZBTB14 | 1:2~1:4 | Negative | Online Inquiry |
KO34787 | ZBTB14 Knockout cell line (HEK293) | Human | ZBTB14 | 1:3~1:6 | Negative | Online Inquiry |
KO34788 | ZBTB14 Knockout cell line (A549) | Human | ZBTB14 | 1:3~1:4 | Negative | Online Inquiry |
ZBTB14 Gene Knockout Cell Lines are engineered cellular models designed to specifically disrupt the expression of the ZBTB14 gene, a key regulator implicated in various cellular processes including transcriptional regulation, immune responses, and differentiation. By utilizing advanced CRISPR-Cas9 gene editing technology, these cell lines allow researchers to study the biological role of ZBTB14 and its contributions to disease mechanisms more effectively.
The primary function of ZBTB14 Gene Knockout Cell Lines lies in enabling the targeted exploration of gene function. The knockout of the ZBTB14 gene leads to significant alterations in cellular signaling pathways and gene expression profiles, providing insights into its involvement in oncogenesis, lineage commitment, and apoptotic processes. This functional elucidation is crucial for understanding how aberrations in this gene may lead to pathological conditions, making these cell lines a valuable tool in both basic and applied research.
In clinical and research settings, ZBTB14 knockout cell lines are particularly advantageous for pharmacological testing and therapeutic development, facilitating the investigation of how targeting ZBTB14 may affect treatment outcomes. They can also be instrumental in the development of new strategies for immunotherapy, given ZBTB14's role in immune cell regulation.
Compared to traditional knockdown approaches that may only temporarily suppress gene expression, our ZBTB14 knockout cell lines offer a permanent and stable genetic modification, allowing for prolonged studies and more robust results. This permanence provides researchers with a reliable model for long-term experiments that explore the implications of ZBTB14 deletion on various cellular behaviors.
Valuable to researchers, clinicians, and pharmaceutical developers alike, ZBTB14 Gene Knockout Cell Lines represent a focused and precise approach to gene function analysis. Incorporating these models into research pipelines empowers users to uncover novel insights into gene-disease relationships and therapeutic options.
Our company specializes in cutting-edge genetic engineering solutions, leveraging years of expertise in cell line development to provide researchers with high-quality, innovative products designed to advance the field of molecular biology and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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