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WDR54 Knockout Cell Lines

Gene: WDR54

Official Full Name: WD repeat domain 54provided by HGNC

Gene Summary: Enables protein homodimerization activity. Involved in negative regulation of receptor internalization; regulation of MAPK cascade; and regulation of epidermal growth factor receptor signaling pathway. Located in intracellular membrane-bounded organelle and vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25246 WDR54 Knockout cell line (HeLa) Human WDR54 1:3~1:6 Negative Online Inquiry
KO25247 WDR54 Knockout cell line (HCT 116) Human WDR54 1:2~1:4 Negative Online Inquiry
KO25248 WDR54 Knockout cell line (HEK293) Human WDR54 1:3~1:6 Negative Online Inquiry
KO25249 WDR54 Knockout cell line (A549) Human WDR54 1:3~1:4 Negative Online Inquiry

Background

WDR54 Gene Knockout Cell Lines are a specialized biological research tool derived from human cell lines in which the WDR54 gene has been inactivated, allowing for the in-depth study of its functional roles in cellular processes. WDR54, a member of the WD repeat protein family, plays crucial roles in regulating various aspects of cellular metabolism, signaling pathways, and gene expression. By employing CRISPR-Cas9 technology, these knockout cell lines facilitate precise genetic modifications, enabling researchers to elucidate the molecular mechanisms underlying WDR54's involvement in cellular functions.

The primary function of these knockout cell lines is to provide a controlled environment to assess the effects of WDR54 deficiency on cell proliferation, differentiation, and response to external stimuli. Researchers can explore the gene's influence on various signaling pathways, thus contributing to a better understanding of its role in diseases such as cancer or neurodegenerative disorders. The applications of WDR54 knockout cell lines extend to drug discovery, where they serve as valuable models for screening potential therapeutic agents that target pathways influenced by WDR54.

One of the significant advantages of utilizing WDR54 Gene Knockout Cell Lines is their specificity and consistency in experimental outcomes. Compared to traditional gene silencing methods, such as RNA interference, CRISPR-based approaches offer more effective and stable gene inactivation. This leads to a more robust model, enhancing the reliability of research findings. Furthermore, the ability to create isogenic cell lines allows for the comparison of phenotypic and genotypic changes with minimal variability, reinforcing the accuracy of experimental results.

For researchers and clinicians, the value of WDR54 Gene Knockout Cell Lines lies in their ability to facilitate high-quality, reproducible studies that advance our understanding of gene function and associated biological processes. As the scientific community increasingly recognizes the importance of gene regulation in health and disease, the need for tools like these knockout cell lines becomes ever more critical.

Our company specializes in providing cutting-edge biological products that empower research and development in various fields. With a strong commitment to quality and innovation, we ensure that our WDR54 Gene Knockout Cell Lines meet the highest standards, supporting the scientific endeavors of our customers worldwide.

Please note that all services are for research use only. Not intended for any clinical use.

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