Gene: UNC5D
Official Full Name: unc-5 netrin receptor Dprovided by HGNC
Gene Summary: Predicted to enable netrin receptor activity. Involved in cell-cell adhesion via plasma-membrane adhesion molecules. Predicted to be located in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26342 | UNC5D Knockout cell line (HEK293) | Human | UNC5D | 1:3~1:6 | Negative | Online Inquiry |
UNC5D Gene Knockout Cell Lines represent a pioneering advancement in the realm of genetic research and cell biology. These specifically engineered cell lines are designed to lack the UNC5D gene, which plays a critical role in neural development and cellular signaling. By knocking out this gene, researchers can delve deeper into understanding its functions and the pathways it influences, particularly in contexts related to neural adhesion and axon guidance.
The utility of UNC5D knockout cell lines lies in their ability to facilitate precise studies regarding gene function and interaction, enabling the exploration of various cellular processes such as apoptosis and neurite outgrowth. The mechanism involves leveraging CRISPR-Cas9 technology, which allows for targeted genome editing, thereby providing researchers with a powerful tool to generate and analyze models that reflect specific phenotypic characteristics related to UNC5D deficiency.
From a scientific perspective, these cell lines are invaluable for applications in neurobiology, developmental biology, and cancer research. They serve as models for studying neurodegenerative diseases, where dysregulation of neural pathways can lead to harmful outcomes. By utilizing UNC5D knockout models, researchers can develop therapeutic strategies and screen potential compounds that might restore normal cell functions or mitigate disease progression.
One of the standout advantages of the UNC5D knockout cell lines is their specificity and reproducibility, which are often lacking in alternative models. Unlike primary cell cultures that can exhibit heterogeneity, these tailored cell lines ensure consistent results across different experiments. Additionally, they provide a streamlined approach for large-scale screenings, thus accelerating the pace of research while minimizing the use of animal models.
For researchers and clinicians, the value of these cell lines extends beyond their experimental utility; they represent a crucial step towards novel discoveries with translational potential. The ability to manipulate cellular environments liberates scientists to innovate in their quest for new therapies.
Our company boasts extensive experience in the development and production of high-quality genetic research tools, underscoring a commitment to empowering the scientific community with cutting-edge solutions. By integrating advanced technology with rigorous quality standards, we ensure that our products, including the UNC5D Gene Knockout Cell Lines, meet the highest expectations of researchers aiming to advance their work in genetics and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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