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TRIM62 Knockout Cell Lines

Gene: TRIM62

Official Full Name: tripartite motif containing 62provided by HGNC

Gene Summary: Enables identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of viral transcription; positive regulation of NF-kappaB transcription factor activity; and positive regulation of antifungal innate immune response. Is active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13051 TRIM62 Knockout cell line (HeLa) Human TRIM62 1:3~1:6 Negative Online Inquiry
KO13052 TRIM62 Knockout cell line (HCT 116) Human TRIM62 1:2~1:4 Negative Online Inquiry
KO13053 TRIM62 Knockout cell line (HEK293) Human TRIM62 1:3~1:6 Negative Online Inquiry
KO13054 TRIM62 Knockout cell line (A549) Human TRIM62 1:3~1:4 Negative Online Inquiry

Background

TRIM62 Gene Knockout Cell Lines represent a groundbreaking advancement in cellular and molecular biology research, providing scientists with invaluable tools for investigating the functional role of the TRIM62 gene. These cell lines have been genetically engineered through CRISPR/Cas9 technology to disrupt the TRIM62 gene, leading to a complete knockout of its expression. By examining these knockout models, researchers can elucidate the pathways in which TRIM62 is involved, particularly its implications in cellular processes such as proliferation, apoptosis, and immune responses.

The primary function of TRIM62 has been linked to various biological functions, including the regulation of protein ubiquitylation, which plays a critical role in protein degradation and cellular homeostasis. In disease contexts, specifically within oncology and immunology, understanding TRIM62's influence on tumorigenesis and immune evasion is vital. The TRIM62 Gene Knockout Cell Lines allow for direct investigation into these mechanisms, facilitating research on targeted therapies and novel treatment strategies.

The scientific importance of these cell lines is underscored by their potential applications in both basic research and clinical settings. From studying gene function and genetic interactions to developing and testing potential therapeutic compounds, these models stand as essential resources for translational research.

Compared to traditional knockdown approaches, which often yield inconsistent gene suppression, TRIM62 Gene Knockout Cell Lines offer a defined and permanent loss of function, providing robust and reproducible results. This reliability enhances the validity of experimental findings and paves the way for more insightful discoveries.

Researchers and clinicians will find significant value in these cell lines due to their ability to streamline various experimental protocols and expedite the investigation of TRIM62-related diseases. With a focus on bolstering scientific innovation, our company delivers unparalleled expertise in the development and optimization of such specialized models, ensuring that our clients have the most advanced tools for their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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