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TPRG1 Knockout Cell Lines

Gene: TPRG1

Official Full Name: tumor protein p63 regulated 1provided by HGNC

Gene Summary: Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13095 TPRG1 Knockout cell line (HCT 116) Human TPRG1 1:2~1:4 Negative Online Inquiry

Background

TPRG1 Gene Knockout Cell Lines are specialized cell lines engineered to have a targeted deletion of the TPRG1 gene, which is known to play a crucial role in various cellular processes, including apoptosis, cell signaling, and tumor suppression. The knockout of this gene allows researchers to investigate the biological functions of TPRG1 in both normal and pathological conditions, leading to a greater understanding of its implications in cancer and other diseases. Through CRISPR/Cas9 technology, these cell lines are created for precise gene editing, ensuring a specific and reproducible genetic alteration.

The key function of TPRG1 Gene Knockout Cell Lines revolves around elucidating the gene's impact on cell cycle regulation and its potential tumor-suppressive properties. Researchers can utilize these cell lines to examine changes in cellular behavior, such as proliferation, apoptosis, and metabolic activity, thereby providing insights into the molecular pathways affected by the absence of TPRG1. This mechanistic understanding is vital for exploring therapeutic strategies aimed at targeting TPRG1-related pathways in cancer treatment.

In scientific research and clinical settings, these cell lines are invaluable for drug discovery, biomarker development, and functional studies related to cancer biology. They provide a robust model for screening compounds that may restore functions typically mediated by TPRG1, thus showcasing their potential in therapeutic interventions.

Compared to traditional methods of studying gene function, such as transgenic models, TPRG1 Gene Knockout Cell Lines offer a quicker and more efficient way to obtain results. Their use significantly lowers the time and resources needed in experiments, enabling researchers to achieve high-throughput screening in a controlled environment. Moreover, these cell lines are readily available, allowing for immediate implementation in ongoing research projects.

Ultimately, TPRG1 Gene Knockout Cell Lines are an indispensable tool for those seeking to deepen their understanding of TPRG1's role in health and disease. With a commitment to quality and innovation, our company specializes in providing cutting-edge biological products that empower researchers and clinicians to make groundbreaking discoveries in the field of molecular biology and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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