Gene: TMEM74
Official Full Name: transmembrane protein 74provided by HGNC
Gene Summary: Predicted to enable transmembrane transporter binding activity. Involved in macroautophagy. Predicted to be located in cytoplasmic vesicle; plasma membrane; and vacuolar membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13295 | TMEM74 Knockout cell line (HEK293) | Human | TMEM74 | 1:3~1:6 | Negative | Online Inquiry |
TMEM74 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the TMEM74 gene's biological functions and its implications in various physiological and pathological conditions. These cell lines are generated through advanced gene-editing techniques, such as CRISPR-Cas9, to create precise deletions in the TMEM74 gene, allowing researchers to observe the effects of its absence on cellular processes and signaling pathways.
The primary function of these knockout cell lines is to enable the investigation of TMEM74’s role in cellular functions, including apoptosis, metabolism, and immune response. By eliminating the gene's expression, researchers can analyze resultant phenotypic changes, leading to critical insights into the gene’s contributions to diseases such as cancer, autoimmune conditions, and metabolic syndromes. This functional assessment is essential for elucidating the underlying mechanisms that govern cellular responses and potential therapeutic targets.
The scientific importance of TMEM74 Gene Knockout Cell Lines lies in their utility as a model system in both basic research and translational studies. They facilitate high-throughput screening of drug candidates and the exploration of gene interactions, thus providing a foundational platform for the development of novel therapeutic strategies.
In comparison to traditional cell lines, the TMEM74 knockout models offer specificity and reproducibility in studying gene function and its associated pathways. Unlike other variants that may exhibit residual gene activity, these knockout lines present a complete absence of TMEM74 expression, ensuring that observed effects are directly attributable to the gene's knockout.
For researchers and clinicians, the value of TMEM74 Gene Knockout Cell Lines is evident in their ability to enhance the understanding of complex biological processes and disease mechanisms, leading to informed decisions in drug development and therapeutic interventions. The generation and quality control of these models underscore a commitment to rigorous scientific standards.
Our company boasts extensive expertise in genetic engineering and cell line development, ensuring that each product, including the TMEM74 Gene Knockout Cell Lines, meets the stringent requirements of modern research, ultimately driving innovation in the biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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