Gene: TMEM100
Official Full Name: transmembrane protein 100provided by HGNC
Gene Summary: Involved in BMP signaling pathway. Located in several cellular components, including endoplasmic reticulum; perikaryon; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13275 | TMEM100 Knockout cell line (HeLa) | Human | TMEM100 | 1:3~1:6 | Negative | Online Inquiry |
KO13276 | TMEM100 Knockout cell line (HEK293) | Human | TMEM100 | 1:3~1:6 | Negative | Online Inquiry |
TMEM100 Gene Knockout Cell Lines are specialized cellular models designed for the functional analysis of the TMEM100 gene, which encodes a transmembrane protein believed to play a crucial role in various cellular processes, including ion transport and cell signaling. By employing CRISPR-Cas9 gene-editing technology, these knockout cell lines exhibit a complete ablation of TMEM100 expression, providing researchers with a powerful tool for investigating its biological functions and implications in disease mechanisms.
The key function of the TMEM100 Gene Knockout Cell Lines is to allow scientists to study the phenotypic consequences of the loss of TMEM100 in an in vitro environment. This enables the examination of alterations in cellular pathways, metabolic activity, and responses to external stimuli, facilitating a deeper understanding of how TMEM100 contributes to physiological and pathological processes. The precise gene modification ensures a robust model system that provides clear insight into the roles of TMEM100, fostering significant advancements in the field of cellular and molecular biology.
From a scientific standpoint, the importance of these cell lines extends beyond basic research. They hold potential applications in drug discovery and therapeutic development, particularly for conditions where TMEM100 is implicated. Researchers can utilize these knockout models to screen for potential pharmacological agents, elucidate the cellular mechanisms underlying diseases, and test therapeutic hypotheses in a controlled environment.
One specific advantage of our TMEM100 Gene Knockout Cell Lines compared to alternatives is their high specificity and reproducibility, which are critical for validation in experimental research. Unlike traditional knockout approaches, our advanced methodology minimizes off-target effects and enhances the reliability of results, thereby strengthening the integrity of experimental conclusions.
For researchers and clinicians, the value of TMEM100 Gene Knockout Cell Lines lies in their ability to contribute to groundbreaking insights into gene function and disease pathology, ultimately paving the way for novel therapeutic strategies. Furthermore, our commitment to providing high-quality, rigorously validated biological products means that users can trust the precision and utility of our offerings. With extensive expertise in gene editing and cell line development, we position ourselves as leaders in facilitating innovative research solutions tailored for the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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