Gene: STXBP6
Official Full Name: syntaxin binding protein 6provided by HGNC
Gene Summary: Enables cadherin binding activity involved in cell-cell adhesion. Predicted to be involved in negative regulation of exocytosis. Located in adherens junction. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27175 | STXBP6 Knockout cell line (HEK293) | Human | STXBP6 | 1:3~1:6 | Negative | Online Inquiry |
KO27176 | STXBP6 Knockout cell line (A549) | Human | STXBP6 | 1:3~1:4 | Negative | Online Inquiry |
STXBP6 Gene Knockout Cell Lines are specialized cell lines developed to facilitate the study of the syntaxin-binding protein 6 (STXBP6), a crucial component involved in vesicle trafficking within secretory pathways. These knockout cell lines are created using advanced CRISPR-Cas9 genome editing technology that effectively disrupts the STXBP6 gene, enabling researchers to elucidate the role of this protein in cellular functions such as neurotransmitter release and membrane fusion.
The key function of STXBP6 includes its interaction with SNARE proteins, which play an essential role in the vesicular transport system. By knocking out this gene, researchers can investigate the downstream effects on synaptic transmission and cellular communication, providing insights into fundamental biological processes as well as the mechanisms underlying various neurodegenerative diseases.
In scientific research, the STXBP6 Gene Knockout Cell Lines are invaluable tools for studying the consequences of STXBP6 deficiency. They have clear applications in academic laboratories focused on neurobiology, cell biology, and biochemistry, as well as in pharmaceutical research aimed at drug discovery for conditions influenced by dysregulated vesicle trafficking.
One key advantage of these cell lines over traditional models is the precision provided by CRISPR-Cas9 technology, which allows for specific gene disruption without affecting neighboring genes. This specificity reduces variability and enhances reproducibility in experiments, making it easier for researchers to draw accurate conclusions about the role of STXBP6.
Furthermore, these knockout lines facilitate investigations into compensatory mechanisms that may arise due to the absence of STXBP6, ultimately aiding in the development of targeted therapeutic approaches.
Our company brings extensive expertise in genetic engineering and cell line development, assuring high-quality and reliable products that meet the evolving needs of the research community. With STXBP6 Gene Knockout Cell Lines, researchers can advance their studies with confidence, unlocking new opportunities in the exploration of cellular mechanisms and potential medical interventions.
Please note that all services are for research use only. Not intended for any clinical use.
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