Gene: STK24
Official Full Name: serine/threonine kinase 24provided by HGNC
Gene Summary: This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34180 | STK24 Knockout cell line (HeLa) | Human | STK24 | 1:3~1:6 | Negative | Online Inquiry |
KO34181 | STK24 Knockout cell line (HCT 116) | Human | STK24 | 1:2~1:4 | Negative | Online Inquiry |
KO34182 | STK24 Knockout cell line (HEK293) | Human | STK24 | 1:3~1:6 | Negative | Online Inquiry |
KO34183 | STK24 Knockout cell line (A549) | Human | STK24 | 1:3~1:4 | Negative | Online Inquiry |
STK24 Gene Knockout Cell Lines are advanced biological tools designed to facilitate the detailed study of the STK24 (Serine/threonine kinase 24) gene's function in cellular processes. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines enable researchers to achieve precise and heritable mutations, effectively silencing the STK24 gene. This knockout mechanism provides a unique opportunity to investigate the gene's regulatory roles in critical cellular pathways, particularly those associated with cell proliferation, apoptosis, and stress responses.
The key function of STK24 Gene Knockout Cell Lines is to serve as a model system where the loss of STK24 activity can be evaluated under various experimental conditions. This functionality allows researchers to explore the implications of STK24 in disease models, including cancer, metabolic disorders, and neurodegenerative diseases. The availability of these knockout cell lines accelerates the scientific process, enabling rapid screening of therapeutic compounds that may target STK24-related pathways.
In clinical and research settings, the importance of STK24 Gene Knockout Cell Lines lies in their ability to provide insights into gene function that have translational significance. By understanding how STK24 influences cellular mechanisms, researchers can develop targeted therapies and improve diagnostic strategies. Compared to traditional gene knockdown methods, these knockout cell lines offer enhanced specificity and permanence, thus yielding more reliable and reproducible results.
The distinct advantages of using STK24 Gene Knockout Cell Lines include their rapid setup, robustness, and cost-effectiveness, making them an invaluable resource for laboratories. Given that the precise modulation of gene activity is critical in the study of complex diseases, these cell lines present a unique selling point over alternatives like conventional RNA interference strategies.
Scientists, clinicians, and industry researchers will find significant value in these gene knockout models as they promote innovation and discovery in genetic research and therapeutic development. Our company is dedicated to providing high-quality biological products, exemplifying expertise in gene editing technologies and their applications in advancing biomolecular research.
Please note that all services are for research use only. Not intended for any clinical use.
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