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SNX2 Knockout Cell Lines

Gene: SNX2

Official Full Name: sorting nexin 2provided by HGNC

Gene Summary: This gene belongs to the sorting nexin family whose members contain the phosphoinositide-binding phox (PX) domain. The encoded protein is a component of the retromer complex which plays a role in protein sorting in the endocytic pathway. This protein may form oligomeric complexes with other family members. Alternate splicing results in multiple transcript variants of this gene. Pseudogenes associated with this gene are located on chromosomes 1 and 7. [provided by RefSeq, May 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35305 SNX2 Knockout cell line (HeLa) Human SNX2 1:3~1:6 Negative Online Inquiry
KO35306 SNX2 Knockout cell line (HCT 116) Human SNX2 1:2~1:4 Negative Online Inquiry
KO35307 SNX2 Knockout cell line (HEK293) Human SNX2 1:3~1:6 Negative Online Inquiry
KO35308 SNX2 Knockout cell line (A549) Human SNX2 1:3~1:4 Negative Online Inquiry

Background

SNX2 Gene Knockout Cell Lines are a sophisticated biotechnological tool engineered to elucidate the functional effects of the SNX2 gene, integral for cellular processes such as endocytosis and intracellular trafficking. SNX2, or sorting nexin 2, is implicated in multiple cellular mechanisms, including the regulation of receptor recycling and signal transduction. The knockout cell lines utilize CRISPR/Cas9 genome editing technology, allowing researchers to create precise mutations that disable the SNX2 gene, thereby enabling studies on the resulting phenotypic changes and pathways influenced by SNX2 activity.

Through the selective deletion of the SNX2 gene, these cell lines provide valuable insights into the gene's role in various physiological and pathological conditions. This is particularly crucial in research areas such as cancer biology, neurodegenerative disorders, and cellular response to stress. By understanding how the absence of SNX2 alters cellular functions, scientists can develop targeted therapies aimed at modulating this pathway, creating opportunities for innovative treatment strategies.

What sets our SNX2 Gene Knockout Cell Lines apart from competitors is their high specificity and efficiency, ensuring minimal off-target effects. This allows for more accurate experimental results, thus enhancing the reliability of research findings. Additionally, our cell lines come with comprehensive support from our expert team, including user-friendly protocols and troubleshooting, facilitating their integration into diverse laboratory workflows.

For researchers and clinicians striving for a deeper understanding of cell signaling and trafficking, the SNX2 Gene Knockout Cell Lines represent an invaluable asset. This product not only expands the frontier of molecular biology research but also underscores our commitment to delivering cutting-edge solutions in genetic engineering. As a leader in biotechnology, our company continuously endeavors to equip the scientific community with innovative tools essential for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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