Gene: SMIM20
Official Full Name: small integral membrane protein 20provided by HGNC
Gene Summary: Involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13918 | SMIM20 Knockout cell line (HeLa) | Human | SMIM20 | 1:3~1:6 | Negative | Online Inquiry |
KO13919 | SMIM20 Knockout cell line (HCT 116) | Human | SMIM20 | 1:2~1:4 | Negative | Online Inquiry |
KO13920 | SMIM20 Knockout cell line (HEK293) | Human | SMIM20 | 1:3~1:6 | Negative | Online Inquiry |
KO13921 | SMIM20 Knockout cell line (A549) | Human | SMIM20 | 1:3~1:4 | Negative | Online Inquiry |
SMIM20 Gene Knockout Cell Lines are genetically modified cell lines in which the SMIM20 gene has been precisely disrupted, leading to the elimination of its functional protein product. This knockout model is crucial for understanding the role of SMIM20 in various biological processes, including cell metabolism, stress response, and development.
The key function of SMIM20 Gene Knockout Cell Lines lies in the absence of SMIM20 protein, which allows researchers to dissect its biological function and its interactions within cellular pathways. By examining these knockout cell lines, scientists can investigate the phenotypic changes that result from the absence of SMIM20, utilizing techniques like flow cytometry, Western blot analysis, and RNA sequencing. Furthermore, the cell lines can be utilized to screen potential therapeutic agents and study the implications of SMIM20 in disease states, particularly in cellular models of cardiovascular and metabolic disorders.
In the research and clinical settings, the value of SMIM20 Gene Knockout Cell Lines is underscored by their potential to advance our understanding of gene function and the molecular basis of diseases. The ability to manipulate specific genes offers unprecedented insights into gene interactions and regulatory networks, making these cell lines an essential tool for basic and applied research.
Compared to alternative models, such as overexpression systems or wild-type cell lines, SMIM20 Gene Knockout Cell Lines provide a direct approach to study loss-of-function scenarios without the confounding effects of overexpression. Additionally, our product is validated for reproducibility and consistency, essential traits for any scientific research endeavor.
Researchers and clinicians leveraging the SMIM20 Gene Knockout Cell Lines stand to gain valuable insights that can lead to novel therapeutic strategies and biomedical advancements. The absence of SMIM20 protein can elucidate underexplored pathways relevant to disease, making it a compelling addition to any research program.
Our company specializes in providing high-quality, reliable biological products, ensuring that our partners have access to cutting-edge tools that accelerate their research objectives. We are dedicated to advancing scientific discovery through innovative solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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