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SLFN13 Knockout Cell Lines

Gene: SLFN13

Official Full Name: schlafen family member 13provided by HGNC

Gene Summary: Enables RNA endonuclease activity. Involved in rRNA catabolic process and tRNA decay. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23957 SLFN13 Knockout cell line (HeLa) Human SLFN13 1:3~1:6 Negative Online Inquiry
KO23958 SLFN13 Knockout cell line (HEK293) Human SLFN13 1:3~1:6 Negative Online Inquiry
KO23959 SLFN13 Knockout cell line (A549) Human SLFN13 1:3~1:4 Negative Online Inquiry

Background

SLFN13 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the Schlafen 13 (SLFN13) gene's role in various biological processes. These cell lines have been meticulously crafted using CRISPR-Cas9 gene editing technology, ensuring a precise and efficient disruption of the SLFN13 gene. The resultant knockout cells serve as pivotal tools for investigating the mechanisms by which SLFN13 influences cellular functions such as immune response, development, and apoptosis.

The key function of SLFN13 gene knockout cell lines lies in their ability to provide researchers with a controlled environment to dissect the impact of SLFN13 deletion across different pathways. For instance, SLFN13 is known to play a role in the modulation of interferon signaling, which is critical for anti-viral immune responses. By studying these knockout lines, scientists can elucidate the gene's contribution to virus-host interactions and its potential implications in infectious disease research and cancer biology.

The scientific importance of SLFN13 knockout cell lines extends to both basic and applied research. Clinically, understanding the functions of SLFN13 can aid in the development of therapeutic strategies that target immune dysregulation, a common predicament in many diseases, including autoimmune disorders and cancers. Furthermore, these cell lines can serve as valuable resources for pharmacological testing and biomarker discovery.

One of the key advantages of our SLFN13 Gene Knockout Cell Lines is their unprecedented specificity and efficiency compared to traditional methods, such as RNA interference, which may result in incomplete gene suppression or off-target effects. Additionally, our cell lines undergo stringent quality control to confirm successful gene knockout and maintain consistent expression profiles, making them highly reliable for experimental reproducibility.

For researchers and clinicians, investing in our SLFN13 gene knockout cell lines means gaining access to robust tools that can accelerate the pace of discovery and innovation in their respective studies. With a commitment to advancing biological research, our company stands at the forefront of cell line development, leveraging cutting-edge technologies to deliver exceptional products that meet evolving research demands.

Please note that all services are for research use only. Not intended for any clinical use.

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