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SLC35E4 Knockout Cell Lines

Gene: SLC35E4

Official Full Name: solute carrier family 35 member E4provided by HGNC

Gene Summary: Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14018 SLC35E4 Knockout cell line (HeLa) Human SLC35E4 1:3~1:6 Negative Online Inquiry
KO14019 SLC35E4 Knockout cell line (HCT 116) Human SLC35E4 1:2~1:4 Negative Online Inquiry
KO14020 SLC35E4 Knockout cell line (HEK293) Human SLC35E4 1:3~1:6 Negative Online Inquiry
KO14021 SLC35E4 Knockout cell line (A549) Human SLC35E4 1:3~1:4 Negative Online Inquiry

Background

SLC35E4 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the functionality of the SLC35E4 gene, which encodes a transporter protein implicated in nucleotide sugar transport across cellular membranes. This unique product serves as a vital tool for researchers studying the physiological role of SLC35E4 and its involvement in various biological processes, including glycosylation patterns, cell signaling, and metabolic pathways.

The key function of the SLC35E4 knockout cell lines is their ability to facilitate the targeted investigation of gene function and the consequent phenotypic effects of its absence. By removing the SLC35E4 gene, researchers can gain insights into how altered nucleotide sugar transport affects cellular biology, particularly in the context of metabolic diseases and cellular development. Moreover, these cell lines allow for enhanced analysis of potential therapeutic strategies that could target the pathways regulated by SLC35E4.

Scientifically, these knockout cell lines are indispensable tools in both basic research and clinical settings. They can be utilized in drug discovery processes, enabling the identification of compounds that may interact with glycosylation pathways or metabolic functions disrupted by the lack of SLC35E4. Furthermore, they serve as models for understanding various pathologies that result from aberrant glycosylation, including congenital disorders and cancers.

What sets SLC35E4 Gene Knockout Cell Lines apart from alternative products is their precise genetic modification, which ensures high specificity and reliability in experimental applications. Unlike generic wild-type cell lines that may introduce variability and confounding factors, these knockout lines provide a controlled environment for reproducible results. This specificity enhances the validity of experimental outcomes, making SLC35E4 knockouts the preferred choice for rigorous scientific investigation.

In conclusion, the SLC35E4 Gene Knockout Cell Lines are a cornerstone for researchers who aim to uncover the nuanced roles of nucleotide sugar transport in cellular dynamics. Their high specificity and functional implications make them desirable for both academic and clinical investigation. Our company is dedicated to providing high-quality biological products that empower researchers to achieve groundbreaking outcomes, backed by decades of expertise in genetic engineering and cell line development.

Please note that all services are for research use only. Not intended for any clinical use.

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