Gene: SLAMF7
Official Full Name: SLAM family member 7provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in T cell activation and immune response. Predicted to act upstream of or within regulation of natural killer cell activation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00357 | SLAMF7 gRNA1-gRNA2 KO plasmid | SLAMF7 | $850 | |||
KO00694 | SLAMF7 Knockout cell line(THP-1) | Human | SLAMF7 | 1:2-1:4 | Negative | Online Inquiry |
KO10005 | SLAMF7 Knockout cell line (A549) | Human | SLAMF7 | 1:3~1:4 | Negative | Online Inquiry |
SLAMF7 Gene Knockout Cell Lines are engineered cellular models created for the specific purpose of studying the SLAMF7 (Signaling Lymphocytic Activation Molecule Family Member 7) gene's biological functions and its role in immune responses. Utilizing advanced CRISPR/Cas9 genome-editing technology, these cell lines are meticulously designed to remove the SLAMF7 gene, allowing researchers to investigate the contributions of this specific molecule in various cellular pathways, particularly those associated with natural killer (NK) cell activation and tumor immune evasion.
The key function of the SLAMF7 Gene Knockout Cell Lines lies in their ability to facilitate the analysis of SLAMF7's role in modulating immune responses. By creating models where SLAMF7 is absent, scientists can study the resultant changes in cellular signaling, gene expression, and protein interactions, thereby gaining insights into SLAMF7's impact on immune surveillance and potential therapeutic applications in oncology and immunology. These cell lines provide a valuable tool for elucidating the molecular mechanisms behind immune modulation and identifying novel therapeutic targets.
The scientific importance of SLAMF7 Knockout Cell Lines extends into both research and clinical settings. They can be employed in drug discovery, specifically targeting cancer treatments that exploit immune checkpoints. Furthermore, these knockout models are pivotal in understanding autoimmunity mechanisms, enabling scientists to follow up on therapeutic approaches aimed at re-establishing effective immune responses.
Compared to alternative models, such as those obtained through traditional knockout strategies or patterns of overexpression, SLAMF7 Gene Knockout Cell Lines offer unparalleled specificity and control. Their rapid generation and the precision of CRISPR/Cas9 technology allow researchers to obtain high-fidelity results while saving valuable time in experimental settings.
For researchers and clinicians seeking to enhance their understanding of immune mechanisms and explore novel treatments, SLAMF7 Gene Knockout Cell Lines are an invaluable resource. Their ability to produce reproducible, relevant data makes them an essential addition to any immunological study.
At [Your Company Name], we pride ourselves on our commitment to providing high-quality biological products that empower researchers and clinicians alike. Our expertise in cell line development and genetic engineering fosters innovation in the field, ensuring that you have access to the most advanced tools available for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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