Home / SETD4 Knockout Cell Lines

SETD4 Knockout Cell Lines

Gene: SETD4

Official Full Name: SET domain containing 4provided by HGNC

Gene Summary: Enables histone H4K20 methyltransferase activity. Predicted to be involved in several processes, including positive regulation of inflammatory response; positive regulation of macromolecule biosynthetic process; and regulation of cell proliferation in bone marrow. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01620 SETD4 Knockout cell line (HeLa) Human SETD4 1:3~1:6 Negative Online Inquiry
KO01621 SETD4 Knockout cell line (HCT 116) Human SETD4 1:2~1:4 Negative Online Inquiry
KO01622 SETD4 Knockout cell line (HEK293) Human SETD4 1:3~1:6 Negative Online Inquiry
KO01623 SETD4 Knockout cell line (A549) Human SETD4 1:3~1:4 Negative Online Inquiry

Background

SETD4 Gene Knockout Cell Lines are a revolutionary tool designed for researchers and clinicians seeking to delve into the intricate functions of the SETD4 gene. These cell lines are engineered to specifically lack the SETD4 gene, allowing for the study of its role in various biological processes, including gene regulation, chromatin remodeling, and the cellular response to stressors. By providing a model system where the specific contribution of SETD4 can be isolated, these knockout lines facilitate a deeper understanding of its implications in human diseases, particularly in cancer research where SETD4 has been implicated in tumorigenesis.

The functionality of SETD4 Gene Knockout Cell Lines stems from their ability to mimic the cellular states present in disease settings where SETD4 is downregulated or mutated. Researchers can investigate the downstream effects of this knockout on epigenetic modulation, gene expression profiles, and cell cycle dynamics. These cell lines have applications in drug discovery, functional genomics, and toxicological assessments, enabling scientists to test the efficacy of therapeutic agents against a SETD4-deficient background.

One of the critical advantages of utilizing SETD4 Gene Knockout Cell Lines is their specificity and reproducibility. Unlike alternatives that might induce generalized knockdowns or use siRNA, these knockout lines provide a stable, long-term genetic modification, reducing variability in experimental results and enhancing the reliability of findings. In addition, these cell lines can be readily integrated into existing research frameworks, providing immediate compatibility with common laboratory protocols.

For researchers and clinicians aiming to uncover the biological roles of epigenetic regulators or their involvement in disease mechanisms, SETD4 Gene Knockout Cell Lines represent an invaluable resource. Their use paves the way for novel insights that could lead to targeted therapeutic interventions or biomarker discovery in clinical settings.

Our company prides itself on pioneering cutting-edge biological products that empower the scientific community. We combine expertise in genetic engineering with a deep commitment to quality and reproducibility, ensuring that you receive the highest standard in research tools.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.