Gene: RNF115
Official Full Name: ring finger protein 115provided by HGNC
Gene Summary: Enables ubiquitin protein ligase activity. Involved in negative regulation of signal transduction; protein ubiquitination; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Is active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27720 | RNF115 Knockout cell line (HeLa) | Human | RNF115 | 1:3~1:6 | Negative | Online Inquiry |
KO27721 | RNF115 Knockout cell line (HCT 116) | Human | RNF115 | 1:2~1:4 | Negative | Online Inquiry |
KO27722 | RNF115 Knockout cell line (HEK293) | Human | RNF115 | 1:3~1:6 | Negative | Online Inquiry |
KO27723 | RNF115 Knockout cell line (A549) | Human | RNF115 | 1:3~1:4 | Negative | Online Inquiry |
RNF115 Gene Knockout Cell Lines are specialized cellular models engineered to lack the RNF115 gene, which encodes a protein involved in ubiquitin-mediated degradation and cellular signaling pathways. By utilizing CRISPR/Cas9 technology, these knockout cell lines facilitate the comprehensive study of RNF115’s role in cellular homeostasis, apoptosis, and various disease mechanisms, including cancer.
The key function of RNF115 knockout cell lines is to provide researchers with a controlled environment to investigate the functional consequences of RNF115 loss, allowing for the analysis of altered protein interactions, signaling cascades, and gene expression profiles. This is instrumental in deciphering complex biological networks and understanding the pathophysiology of human diseases.
In terms of scientific importance, RNF115 knockout cell lines are invaluable in preclinical research settings, particularly for developing targeted therapies and biomarker identification. They enable elucidation of potential therapeutic targets and provide a platform for drug screening, enhancing our understanding of drug efficacy and resistance mechanisms.
What sets RNF115 Gene Knockout Cell Lines apart from other cellular models is their precision and reliability. Conventional knockout methods often lead to off-target effects or incomplete gene disruption. In contrast, our product offers high specificity and efficiency due to its advanced CRISPR engineering techniques. Additionally, these cell lines are rigorously validated, ensuring reproducible results for your research needs.
For researchers and clinicians, investing in RNF115 Gene Knockout Cell Lines translates to more robust experimental data and accelerated discovery processes. This product is essential for those aiming to make significant contributions to molecular biology and therapeutic development.
Our company prides itself on extensive expertise in genetic modification technologies, offering a diverse range of quality biological products that empower scientific advancement. By choosing our RNF115 Gene Knockout Cell Lines, you gain access to cutting-edge tools fostered by a commitment to excellence in biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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