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RFPL3 Knockout Cell Lines

Gene: RFPL3

Official Full Name: ret finger protein like 3provided by HGNC

Gene Summary: Predicted to enable protein homodimerization activity; protein kinase binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of autophagy; positive regulation of canonical NF-kappaB signal transduction; and regulation of viral entry into host cell. Predicted to be located in nucleus. Predicted to be active in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31587 RFPL3 Knockout cell line (HEK293) Human RFPL3 1:3~1:6 Negative Online Inquiry

Background

RFPL3 Gene Knockout Cell Lines are specialized, genetically engineered models that have been developed to facilitate the study of the RFPL3 gene and its associated biological pathways. These cell lines have undergone targeted gene deletions using advanced CRISPR/Cas9 technology to achieve precise knockout of the RFPL3 gene. This disruption allows researchers to investigate the functional role of RFPL3, a gene implicated in various cellular processes including proliferation, differentiation, and apoptosis.

The key mechanism by which RFPL3 Gene Knockout Cell Lines operate involves the absence of RFPL3 protein, enabling scientists to compare the cellular behavior of knockout cells to their wild-type counterparts. By analyzing changes in gene expression, signaling pathways, and cell-phenotypic characteristics, researchers can uncover the biological implications of RFPL3 deficiency in diverse contexts, including cancer biology, regenerative medicine, and developmental studies.

This product holds significant scientific importance as it provides a critical tool for both basic and translational research. Clinically, these cell lines can help identify potential therapeutic targets and elucidate mechanisms of disease related to RFPL3 dysregulation. They are particularly valuable in drug discovery and assay development, where understanding gene function at a cellular level is crucial.

Compared to alternative cell lines that may not precisely mimic the mutation of interest, RFPL3 Gene Knockout Cell Lines offer unparalleled specificity and confidence in experimental outcomes. The precise nature of the knockout ensures that findings are directly attributable to the absence of RFPL3.

For researchers and clinicians, these cell lines represent a powerful resource that can accelerate discoveries and promote innovative therapeutics. With our deep expertise in genetic engineering and cell line development, our company is committed to providing high-quality biological products that meet the needs of modern research and clinical applications. Investing in RFPL3 Gene Knockout Cell Lines can significantly enhance your research capabilities, enriching your scientific endeavors with reliable and relevant findings.

Please note that all services are for research use only. Not intended for any clinical use.

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