Gene: RASSF5
Official Full Name: Ras association domain family member 5provided by HGNC
Gene Summary: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08964 | RASSF5 Knockout cell line (HeLa) | Human | RASSF5 | 1:3~1:6 | Negative | Online Inquiry |
KO08965 | RASSF5 Knockout cell line (HCT 116) | Human | RASSF5 | 1:2~1:4 | Negative | Online Inquiry |
KO08966 | RASSF5 Knockout cell line (HEK293) | Human | RASSF5 | 1:3~1:6 | Negative | Online Inquiry |
KO08967 | RASSF5 Knockout cell line (A549) | Human | RASSF5 | 1:3~1:4 | Negative | Online Inquiry |
RASSF5 Gene Knockout Cell Lines are specialized biological tools developed for advanced research in cell signaling and cancer biology. These cell lines are engineered to lack the RASSF5 gene, which encodes a member of the Ras association domain family implicated in regulating cell cycle progression, apoptosis, and tumor growth. By studying these knockout cell lines, researchers can elucidate the functional role of RASSF5 in cancer pathogenesis and investigate its potential as a therapeutic target.
The primary mechanism underlying the utility of RASSF5 Gene Knockout Cell Lines lies in their ability to facilitate the understanding of cellular processes that are disrupted in malignancy. By comparing the biological behaviors of RASSF5-deficient cells with wild-type counterparts, researchers can gain insights into pathways involved in cancer metastasis, cell proliferation, and resistance to apoptosis. These models can also be pivotal in drug screening and the development of targeted therapies, allowing scientists to observe the effects of various treatments on RASSF5-null cells and their functional resemblance to tumorigenic states.
The scientific importance of RASSF5 Gene Knockout Cell Lines extends into both basic and applied research domains, enabling exploration of therapeutic avenues in precision medicine. Compared to standard cell lines, these knockout models offer a distinct advantage in dissecting the roles of specific genes in disease contexts, providing a clearer picture of gene function devoid of compensatory mechanisms that may obscure results.
Researchers and clinicians seeking to optimize their studies will find value in the precision and specificity offered by RASSF5 Gene Knockout Cell Lines. They stand out not only as robust models for probing gene function but also as vital resources for understanding tumor biology. Our company specializes in providing high-quality biological research tools that support cutting-edge science and enhance research reliability.
Please note that all services are for research use only. Not intended for any clinical use.
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