Home / PRSS8 Knockout Cell Lines

PRSS8 Knockout Cell Lines

Gene: PRSS8

Official Full Name: serine protease 8provided by HGNC

Gene Summary: This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35872 PRSS8 Knockout cell line (HCT 116) Human PRSS8 1:2~1:4 Negative Online Inquiry

Background

PRSS8 Gene Knockout Cell Lines are genetically engineered cell lines in which the PRSS8 gene has been specifically disrupted, leading to the loss of its functional protein product, a serine protease implicated in various physiological processes and disease states. By employing advanced CRISPR/Cas9 technology, these cell lines provide a powerful tool for researchers to investigate the biological roles of the PRSS8 gene in development, immunity, and tumorigenesis.

The primary function of the PRSS8 gene relates to its involvement in the activation of other proteolytic enzyme cascades critical for maintaining cellular homeostasis and mediating inflammatory responses. By utilizing these knockout cell lines, researchers can delineate the biochemical pathways influenced by PRSS8, identifying potential molecular targets for therapeutic interventions in conditions such as cancer, autoimmunity, and infectious diseases.

In scientific research and clinical applications, PRSS8 Gene Knockout Cell Lines serve as a vital resource for in vitro studies that assess gene function, protein interactions, and signaling pathways. Their utility extends to drug discovery, as these cell lines enable the validation of novel compounds targeting PRSS8-related pathways. Moreover, the ability to compare knockout lines with wild-type counterparts enhances our understanding of gene functions in a controlled environment.

What sets our PRSS8 Gene Knockout Cell Lines apart is their robustness, consistency, and the comprehensive characterization data provided alongside them, ensuring researchers have access to reliable and reproducible results. By minimizing experimental variability, these cell lines facilitate high-throughput screening and complex assay setups, streamlining the research process.

For researchers and clinicians striving to advance their work, the inclusion of PRSS8 Gene Knockout Cell Lines in their investigations can significantly accelerate the pace of discovery, ultimately leading to critical breakthroughs in understanding disease mechanisms. Our company specializes in high-quality biological products and has a proven track record of providing innovative solutions to the scientific community, ensuring that you have the tools necessary for cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.