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PPA2 Knockout Cell Lines

Gene: PPA2

Official Full Name: inorganic pyrophosphatase 2provided by HGNC

Gene Summary: The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27882 PPA2 Knockout cell line (HeLa) Human PPA2 1:3~1:6 Negative Online Inquiry
KO27883 PPA2 Knockout cell line (HCT 116) Human PPA2 1:2~1:4 Negative Online Inquiry
KO27884 PPA2 Knockout cell line (HEK293) Human PPA2 1:3~1:6 Negative Online Inquiry

Background

PPA2 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed to facilitate in-depth genetic research. These cell lines have been engineered to disrupt the expression of the PPA2 gene, which encodes for the pyrophosphate-activated protein phosphatase, a critical enzyme involved in various metabolic pathways including phosphate homeostasis and energy metabolism. By creating a knockout of this gene, researchers can closely study the resultant phenotypic changes and elucidate the role of PPA2 in cellular processes.

The primary function of the PPA2 Gene Knockout Cell Lines is to serve as a model for understanding the consequences of genetic loss within a controlled environment. These cell lines enable scientists to investigate downstream signaling pathways and metabolic alterations that may arise from the absence of the PPA2 protein. Additionally, researchers can utilize these models to screen potential therapeutic agents that could rectify metabolic dysfunctions related to PPA2 deficiencies.

The scientific importance of the PPA2 Gene Knockout Cell Lines is underscored by their potential applications in both basic and translational research. In clinical settings, the insights gained from these cell lines could lead to breakthroughs in understanding diseases associated with metabolic dysregulation, such as diabetes and certain types of cancer.

What sets our PPA2 Gene Knockout Cell Lines apart from alternatives is their rigorous validation and characterization, ensuring reproducibility and reliability in experimental outcomes. They provide a targeted approach for gene function studies, minimizing off-target effects often encountered with less precise genetic engineering techniques.

For researchers and clinicians alike, the PPA2 Gene Knockout Cell Lines offer invaluable insights into gene function, serving as a cornerstone for future discoveries and advanced therapeutic approaches. Our company has a proven track record in developing innovative biological tools, ensuring that our products are accompanied by extensive scientific support and guidance. By choosing our PPA2 Gene Knockout Cell Lines, you are investing in a reliable resource that will aid in your pursuit of scientific excellence and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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