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PLXDC1 Knockout Cell Lines

Gene: PLXDC1

Official Full Name: plexin domain containing 1provided by HGNC

Gene Summary: Predicted to be involved in angiogenesis. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15015 PLXDC1 Knockout cell line (HCT 116) Human PLXDC1 1:2~1:4 Negative Online Inquiry
KO15016 PLXDC1 Knockout cell line (HEK293) Human PLXDC1 1:3~1:6 Negative Online Inquiry

Background

PLXDC1 Gene Knockout Cell Lines are specialized cell lines engineered to lack the expression of the PLXDC1 gene, a critical component in various cellular processes, including cell adhesion and migration. By employing advanced CRISPR/Cas9 gene-editing technology, these knockout cell lines enable researchers to investigate the functional consequences of PLXDC1 deletion in model organisms. The absence of this gene facilitates examination of its role within physiological and pathological contexts, particularly in cancer biology and developmental studies.

The primary mechanism at play involves the use of targeted gene disruption to elucidate PLXDC1's contributions to cell signaling pathways and extracellular matrix interactions. Researchers can manipulate these cells to study how the loss of PLXDC1 affects cellular behavior, gene expression profiles, and interaction with surrounding tissue environments. This function is pivotal in understanding the mechanisms of tumor progression, metastasis, and tissue development, rendering these cell lines significant tools in both basic and applied research.

In clinical settings and research laboratories, the application of PLXDC1 Gene Knockout Cell Lines is invaluable for their ability to provide insights into target-specific drug development and disease modeling. Unlike traditional knockdown approaches, which can result in incomplete gene silencing, knockout cell lines provide clear delineation of the gene's functional role, offering more reproducible and reliable experimental outcomes.

What sets our product apart is the rigor of our engineering process and the extensive validation of our knockout models. By ensuring a complete knockout of PLXDC1 and characterizing their phenotypic outcomes, we provide researchers with confidence in the reliability and applicability of their results. Furthermore, our cell lines are manufactured under strict quality control measures, positioning them as the optimal choice in a competitive market.

We pride ourselves on our commitment to excellence in biological products and our extensive experience in cellular engineering. With a focus on advancing scientific discovery, our PLXDC1 Gene Knockout Cell Lines empower researchers and clinicians alike to unlock the complexities of cellular function, fostering innovation and progress in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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