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PLPBP Knockout Cell Lines

Gene: PLPBP

Official Full Name: pyridoxal phosphate binding proteinprovided by HGNC

Gene Summary: This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31065 PLPBP Knockout cell line (HeLa) Human PLPBP 1:3~1:6 Negative Online Inquiry
KO31066 PLPBP Knockout cell line (HCT 116) Human PLPBP 1:2~1:4 Negative Online Inquiry
KO31067 PLPBP Knockout cell line (HEK293) Human PLPBP 1:3~1:6 Negative Online Inquiry
KO31068 PLPBP Knockout cell line (A549) Human PLPBP 1:3~1:4 Negative Online Inquiry

Background

PLPBP Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the effects of the PLPBP gene, which plays a crucial role in various biological processes, including the regulation of lipid metabolism and neural function. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide a powerful tool for researchers to elucidate the gene's biological function and dissect its involvement in disease mechanisms.

The key function of PLPBP Gene Knockout Cell Lines lies in their ability to systematically eliminate the expression of the PLPBP gene, allowing for detailed investigation into its pathways and interactions. By observing the phenotypic and functional changes in the knockout cells compared to wild-type controls, scientists can gain insights into the gene's contributions to cellular processes such as energy metabolism, inflammation, and neuroprotection.

In clinical and research settings, these knockout cell lines facilitate the exploration of potential therapeutic targets for diseases linked to abnormal lipid metabolism and neurodegenerative disorders. They serve as invaluable tools for drug discovery, helping to identify novel compounds that can modulate the effects of PLPBP and potentially lead to innovative treatment strategies.

One of the distinct advantages of PLPBP Gene Knockout Cell Lines is their unparalleled specificity and reproducibility, enabling precise gene editing outcomes that are often difficult to achieve with alternative methods. This specificity enhances the reliability of experimental results, making them crucial for high-stakes scientific inquiries.

Researchers and clinicians are increasingly valuing the PLPBP Gene Knockout Cell Lines in their work due to their potential to accelerate discovery and improve our understanding of complex biological systems. With our commitment to providing high-quality biological products backed by cutting-edge technology, our company leverages extensive expertise in gene editing and cell line development to deliver solutions that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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