Gene: PIM2
Official Full Name: Pim-2 proto-oncogene, serine/threonine kinaseprovided by HGNC
Gene Summary: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06927 | PIM2 Knockout cell line (HeLa) | Human | PIM2 | 1:3~1:6 | Negative | Online Inquiry |
KO06928 | PIM2 Knockout cell line (HCT 116) | Human | PIM2 | 1:2~1:4 | Negative | Online Inquiry |
KO06929 | PIM2 Knockout cell line (HEK293) | Human | PIM2 | 1:3~1:6 | Negative | Online Inquiry |
KO06930 | PIM2 Knockout cell line (A549) | Human | PIM2 | 1:3~1:4 | Negative | Online Inquiry |
PIM2 Gene Knockout Cell Lines are genetically modified cell lines designed to provide a powerful tool for the study of the PIM2 gene's role in cellular processes and disease mechanisms. Utilizing CRISPR/Cas9 technology, these cell lines have been engineered to completely disrupt the PIM2 gene, allowing researchers to investigate the functional consequences of its loss. The PIM2 gene encodes a serine/threonine kinase that has been implicated in a variety of biological functions, including cellular proliferation, apoptosis, and the regulation of cell metabolism. By creating knockout lines, researchers can effectively elucidate the pathways and interactions associated with PIM2 activity in a controlled environment.
The mechanisms that underlie the functions of PIM2 involve its role in the phosphorylation of pathway-specific substrates, which ultimately influence crucial processes such as tumorigenesis and cellular survival. Thus, these knockout cell lines are invaluable for cancer research, where understanding the specific contributions of PIM2 to tumor growth and resistance to therapy can lead to novel therapeutic strategies.
In comparative terms, PIM2 Gene Knockout Cell Lines stand out due to their high specificity and precision in gene editing, enabling researchers to establish confidence in their results. Unlike traditional methods of gene knockdown, which may yield partial results and can often be affected by off-target effects, these knockout lines present a clean slate, facilitating thorough investigations.
For researchers and clinicians involved in cancer biology, developmental studies, and therapeutic discovery, the PIM2 Gene Knockout Cell Lines offer an unparalleled opportunity to advance understanding of gene function in a highly relevant context. With their ease of use and reliability, these cell lines can significantly enhance experimental reproducibility and provide insights that could translate into clinical applications.
Our company has extensive experience in genetic engineering and is committed to providing premium biological products like the PIM2 Gene Knockout Cell Lines that meet the highest standards of quality and reliability. We support researchers in their quest to unlock the complexities of gene function with advanced solutions tailored to their experimental needs.
Please note that all services are for research use only. Not intended for any clinical use.
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