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PHF14 Knockout Cell Lines

Gene: PHF14

Official Full Name: PHD finger protein 14provided by HGNC

Gene Summary: Enables histone binding activity. Predicted to be involved in several processes, including germinal center B cell differentiation; lung development; and negative regulation of mesenchymal cell proliferation involved in lung development. Located in chromatin; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32935 PHF14 Knockout cell line (HeLa) Human PHF14 1:3~1:6 Negative Online Inquiry
KO32936 PHF14 Knockout cell line (HCT 116) Human PHF14 1:2~1:4 Negative Online Inquiry
KO32937 PHF14 Knockout cell line (HEK293) Human PHF14 1:3~1:6 Negative Online Inquiry
KO32938 PHF14 Knockout cell line (A549) Human PHF14 1:3~1:4 Negative Online Inquiry

Background

PHF14 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the investigation of the PHF14 gene's role in various cellular processes. These cell lines exhibit a complete ablation of the PHF14 gene, enabling researchers to study gene function, signaling pathways, and cellular behaviors in a controlled environment. The knockout mechanism is achieved through advanced gene-editing technologies, such as CRISPR/Cas9, which ensure precise deletion of the targeted gene, allowing for robust exploration of its biological significance.

The primary function of PHF14 Gene Knockout Cell Lines is to provide researchers with a reliable model to elucidate the gene's contribution to processes such as chromatin remodeling, transcriptional regulation, and potential implications in oncogenesis. By analyzing these cell lines, scientists can gain insights into the gene's involvement in various diseases, particularly cancers where dysregulation of gene expression is critical. Their utility spans a broad range of applications, from basic research to drug development, making them an indispensable tool in both academic and clinical settings.

Compared to traditional cell models, PHF14 Gene Knockout Cell Lines offer unique advantages, including high specificity, reproducibility, and the ability to simulate pathophysiological conditions more accurately. This specificity allows for clearer interpretation of gene function and its downstream effects, therefore providing more reliable data for hypothesis testing. Furthermore, these cell lines are readily available and can be easily integrated into existing laboratory workflows, reducing setup time and expediting research timelines.

For researchers and clinicians focused on gene function and disease mechanisms, the PHF14 Gene Knockout Cell Lines provide a compelling value proposition. These models not only enhance the understanding of genetic contributions to complex biological processes but also serve as a foundation for the development of targeted therapies. Our company specializes in providing high-quality biological products, backed by extensive expertise in molecular biology and gene editing, ensuring that researchers have access to the tools they need to unlock new scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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