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PDLIM1 Knockout Cell Lines

Gene: PDLIM1

Official Full Name: PDZ and LIM domain 1provided by HGNC

Gene Summary: This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33565 PDLIM1 Knockout cell line (HeLa) Human PDLIM1 1:3~1:6 Negative Online Inquiry
KO33566 PDLIM1 Knockout cell line (HCT 116) Human PDLIM1 1:2~1:4 Negative Online Inquiry
KO33567 PDLIM1 Knockout cell line (HEK293) Human PDLIM1 1:3~1:6 Negative Online Inquiry
KO33568 PDLIM1 Knockout cell line (A549) Human PDLIM1 1:3~1:4 Negative Online Inquiry

Background

PDLIM1 Gene Knockout Cell Lines are engineered cellular models generated through the precise deletion of the PDLIM1 gene, which encodes a scaffold protein involved in various signal transduction pathways. By utilizing cutting-edge CRISPR-Cas9 technology, these cell lines enable researchers to dissect the cellular functions and molecular mechanisms regulated by PDLIM1. The knockout model allows for the assessment of phenotypic changes, providing insights into the role of this gene in cellular processes such as proliferation, apoptosis, and migration.

The primary function of PDLIM1 is to organize protein-protein interactions, influencing signaling pathways that are critical for proper cellular responses. The knockout of this gene facilitates the exploration of its contributions to diseases such as cancer, where aberrant signaling is a hallmark. Additionally, researchers can utilize these cell lines in drug discovery and development, as understanding PDLIM1’s role may unveil new therapeutic targets.

The scientific importance of PDLIM1 Gene Knockout Cell Lines lies in their versatility across various research fields, from oncology to cardiovascular and neurological studies. Compared to traditional cell models, these knockout lines offer enhanced specificity and relevance, allowing for more accurate modeling of human diseases.

One of the significant advantages of our PDLIM1 Gene Knockout Cell Lines is their validation against extensive benchmarks, ensuring consistent performance and reproducibility in experiments. This reliability, paired with the ease of use and adaptability to high-throughput screening, makes them a superior choice for researchers seeking to accelerate their projects without compromising on quality.

Ultimately, these specialized cell lines serve as valuable tools for elucidating the complex biological roles of PDLIM1, empowering researchers and clinicians alike to drive innovation in their fields. Our company, with its commitment to excellence in biotechnological solutions, leverages advanced genetic engineering techniques to provide high-quality biological products that support cutting-edge research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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