Gene: OR4Q3
Official Full Name: olfactory receptor family 4 subfamily Q member 3provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25837 | OR4Q3 Knockout cell line (HeLa) | Human | OR4Q3 | 1:3~1:6 | Negative | Online Inquiry |
KO25838 | OR4Q3 Knockout cell line (HCT 116) | Human | OR4Q3 | 1:2~1:4 | Negative | Online Inquiry |
KO25839 | OR4Q3 Knockout cell line (A549) | Human | OR4Q3 | 1:3~1:4 | Negative | Online Inquiry |
OR4Q3 Gene Knockout Cell Lines represent a pioneering advancement in genetic research and molecular biology, specifically designed to eliminate the OR4Q3 gene's expression in host cells. This innovative product utilizes CRISPR-Cas9 technology to precisely delete the target gene, allowing researchers to study the functional implications of OR4Q3 loss in cellular processes. By creating a model system where the OR4Q3 gene is absent, scientists can dissect its role in various physiological pathways and disease states, leading to potential insights into its contributions to fundamental biological mechanisms.
The key feature of OR4Q3 Gene Knockout Cell Lines lies in their ability to facilitate targeted investigations into gene function through comparative analyses with wild-type or control cell lines. The knockout mechanism operates via the Cas9 endonuclease creating double-strand breaks at specific genomic locations, which are then repaired through non-homologous end joining, leading to insertions or deletions that effectively disrupt gene expression. This precision enables researchers to study the consequences of gene inactivation in a controlled environment, thereby enhancing the reproducibility and reliability of experimental outcomes.
In terms of scientific importance, these knockout cell lines serve as invaluable tools for a variety of applications, including drug discovery, gene function analysis, and the development of therapeutic strategies. Their utility extends to both in vitro assays and the exploration of gene-environment interactions. Moreover, these models hold promise for preclinical studies aimed at understanding the role of the OR4Q3 gene in specific pathologies, such as metabolic disorders or cancer.
Compared to other genetic manipulation tools, OR4Q3 Gene Knockout Cell Lines offer unique advantages, including high specificity, reduced off-target effects, and the elimination of time-consuming screening processes often required in traditional methods. This allows researchers to accelerate their experiments and obtain meaningful data faster than with other available alternatives.
The value of the OR4Q3 Gene Knockout Cell Lines lies in their ability to provide researchers, clinicians, and biopharmaceutical companies with a robust platform for understanding gene function and its implications in health and disease. Their potential to drive innovative research and contribute to cutting-edge therapeutic developments makes them an essential asset in modern biological science.
Our company prides itself on delivering high-quality biological products backed by extensive expertise in genetic engineering and cell line development, ensuring that our offerings meet the diverse needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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