Gene: OR14L1
Official Full Name: olfactory receptor family 14 subfamily L member 1provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15452 | OR14L1 Knockout cell line (HeLa) | Human | OR14L1 | 1:3~1:6 | Negative | Online Inquiry |
KO15453 | OR14L1 Knockout cell line (HCT 116) | Human | OR14L1 | 1:2~1:4 | Negative | Online Inquiry |
KO15454 | OR14L1 Knockout cell line (HEK293) | Human | OR14L1 | 1:3~1:6 | Negative | Online Inquiry |
KO15455 | OR14L1 Knockout cell line (A549) | Human | OR14L1 | 1:3~1:4 | Negative | Online Inquiry |
OR14L1 Gene Knockout Cell Lines are specialized cellular models developed to investigate the functional role of the OR14L1 gene, known for its involvement in olfactory signaling pathways and its potential implications in neurobiology and cancer research. These cell lines have been meticulously engineered using CRISPR/Cas9 technology to create a precise knockout of the OR14L1 gene, enabling researchers to elucidate its role in cellular processes and disease mechanisms.
The primary function of OR14L1 gene knockout is to serve as a powerful tool for functional genomics, allowing scientists to study the absence of OR14L1 and its downstream effects on signaling pathways, gene expression, and cellular behavior. By employing these knockout cell lines, researchers can investigate the gene’s contribution to olfactory receptor function, neuronal signaling, and even metabolic responses. This functional insight is paramount in the context of disorders involving sensory perception or tumorigenesis, as well as assessing drug interactions and therapeutic targets.
In clinical and research settings, OR14L1 gene knockout cell lines stand as critical assets for developing personalized medicine approaches and conducting high-throughput screening of pharmaceutical compounds that may interface with olfactory signaling. Compared to traditional methods such as RNA interference, gene knockout offers a more durable and complete deficiency, eliminating redundancy and compensatory mechanisms that could obscure results.
What sets our OR14L1 gene knockout cell lines apart is their reliability and quality assurance, achieved through our proprietary validation processes. Each cell line undergoes extensive characterization to confirm successful gene knockout and consistent behavior across generations, ensuring reproducibility in experimental conditions.
For researchers, clinicians, and pharmaceutical developers focusing on genetic pathways that influence sensory functions or cancer biology, our OR14L1 gene knockout cell lines provide unparalleled value through their ability to deliver clear, actionable data. By investing in this innovative product, users can pave the way for breakthroughs in understanding gene function and developing targeted therapies.
With a solid background in genetic research and an unwavering commitment to quality, our company is dedicated to providing cutting-edge biological products that empower the scientific community in their quest to unravel complex biological phenomena.
Please note that all services are for research use only. Not intended for any clinical use.
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