Gene: NUCB1
Official Full Name: nucleobindin 1provided by HGNC
Gene Summary: This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36298 | NUCB1 Knockout cell line (HeLa) | Human | NUCB1 | 1:3~1:6 | Negative | Online Inquiry |
KO36299 | NUCB1 Knockout cell line (HCT 116) | Human | NUCB1 | 1:2~1:4 | Negative | Online Inquiry |
KO36300 | NUCB1 Knockout cell line (HEK293) | Human | NUCB1 | 1:3~1:6 | Negative | Online Inquiry |
KO36301 | NUCB1 Knockout cell line (A549) | Human | NUCB1 | 1:3~1:4 | Negative | Online Inquiry |
NUCB1 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of the nucleobindin-1 (NUCB1) protein, a key component implicated in calcium signaling and physiology. By employing CRISPR-Cas9 technology, these cell lines have been meticulously created to disrupt the NUCB1 gene’s function, providing researchers with an invaluable tool to investigate the role of NUCB1 in various biological processes and pathologies, including neurodegenerative diseases and cancer.
The primary function of these knockout cell lines is to serve as a comparative model against wild-type cells, enabling detailed analyses of cellular responses without the influence of the NUCB1 protein. Researchers can delve into mechanisms of calcium homeostasis, gene expression regulation, and the interaction of NUCB1 with other signaling pathways. This can yield insights into how the absence of NUCB1 contributes to disease progression and may facilitate the identification of novel therapeutic targets.
In both research and clinical settings, NUCB1 Gene Knockout Cell Lines stand out due to their capability to replicate human disease models closely, thus enhancing the translation of laboratory findings to clinical applications. Their ability to provide a controlled environment for rigorous experimentation makes them essential for drug discovery, validation of biomarker candidates, and understanding complex cellular behaviors.
The advantages of NUCB1 Gene Knockout Cell Lines include their ease of use and robust consistency compared to alternative models like transient knockdown approaches, which may not provide long-term insights due to variability. This stability allows for repeatable experiments over extended periods, giving researchers confidence in their findings.
For scientists and clinicians keen on advancing their understanding of NUCB1-related pathways, these knockout cell lines represent an unparalleled resource. By facilitating groundbreaking research and accelerating the development of innovative therapies, NUCB1 Gene Knockout Cell Lines are integral to the scientific community.
Our company, with its proven expertise in cell line development and molecular biology, is dedicated to empowering researchers with high-quality biological products that drive scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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