Gene: NRDC
Official Full Name: nardilysin convertaseprovided by HGNC
Gene Summary: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01830 | NRDC Knockout cell line (HeLa) | Human | NRDC | 1:3~1:6 | Negative | Online Inquiry |
KO01831 | NRDC Knockout cell line (HCT 116) | Human | NRDC | 1:2~1:4 | Negative | Online Inquiry |
KO01832 | NRDC Knockout cell line (HEK293) | Human | NRDC | 1:3~1:6 | Negative | Online Inquiry |
KO01833 | NRDC Knockout cell line (A549) | Human | NRDC | 1:3~1:4 | Negative | Online Inquiry |
NRDC Gene Knockout Cell Lines are specifically engineered cell lines designed to facilitate the study of gene function by enabling researchers to create precise gene knockout models. These models are invaluable tools in biological and medical research, allowing scientists to disrupt specific genes and observe the resulting phenotypic changes in a controlled environment. By employing cutting-edge CRISPR/Cas9 technology, these cell lines ensure high efficiency in gene disruption, achieving consistent knockout rates with minimal off-target effects.
The key mechanisms that underlie the functionality of NRDC Gene Knockout Cell Lines involve the targeted introduction of double-strand breaks into the genomic DNA, which subsequently leads to insertions or deletions (indels) during the DNA repair process. This targeted approach not only ensures specificity but also allows researchers to study the roles of specific genes in cellular pathways, drug resistance, or metabolic processes, providing insights that are crucial for understanding cellular mechanisms in health and disease.
The scientific importance of these gene knockout cell lines cannot be overstated, as they have broad applications in various research contexts, ranging from cancer biology and neurobiology to regenerative medicine. Clinicians and researchers alike benefit from the ability to model human diseases more accurately, paving the way for the discovery of new therapeutic strategies and enhancing our understanding of complex biological processes.
Compared to traditional gene knockout methods, the NRDC Gene Knockout Cell Lines offer several competitive advantages, including faster turnaround times for model generation, higher specificity, and a user-friendly platform that integrates seamlessly into existing workflows. This makes our product not only a valuable asset for those in basic research but also for translational medicine, where understanding gene function is crucial for developing new treatments.
In summary, the NRDC Gene Knockout Cell Lines represent a powerful innovation in genetic research, allowing scientists to unlock the mysteries of gene function with unprecedented precision. Our company boasts extensive expertise in genetic engineering and a commitment to advancing scientific discovery, providing cutting-edge products that support research excellence and the pursuit of new therapeutic frontiers.
Please note that all services are for research use only. Not intended for any clinical use.
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