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NFIA Knockout Cell Lines

Gene: NFIA

Official Full Name: nuclear factor I Aprovided by HGNC

Gene Summary: This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01727 NFIA Knockout cell line (HeLa) Human NFIA 1:3~1:6 Negative Online Inquiry
KO01728 NFIA Knockout cell line (HCT 116) Human NFIA 1:2~1:4 Negative Online Inquiry
KO01729 NFIA Knockout cell line (HEK293) Human NFIA 1:3~1:6 Negative Online Inquiry
KO01730 NFIA Knockout cell line (A549) Human NFIA 1:3~1:4 Negative Online Inquiry

Background

NFIA Gene Knockout Cell Lines represent a pinnacle of genetic research tools, specifically engineered to elucidate the functional role of the NFIA (Nuclear Factor I A) gene in various biological processes. These cell lines are meticulously designed to abrogate the expression of the NFIA gene, allowing researchers to investigate the gene's roles in cellular differentiation, development, and pathological conditions. By employing CRISPR/Cas9 gene-editing technology, NFIA knockout cell lines provide a robust model for examining the downstream effects of NFIA loss on gene expression, signaling pathways, and cellular physiology.

The primary function of NFIA pertains to its role as a transcription factor that influences gene expression involved in neurogenesis and gliogenesis. Understanding how NFIA contributes to these processes is crucial, as dysregulation has been linked to neurodevelopmental disorders and certain forms of cancer. Researchers utilizing these knockout cell lines can gain insights into NFIA's involvement in cellular mechanisms, facilitating the development of targeted therapies and novel interventions in clinical settings.

What sets NFIA Gene Knockout Cell Lines apart from other gene-editing models is the specificity and reliability of the knockout method. The CRISPR/Cas9 approach ensures precise gene disruption, enabling higher fidelity results compared to traditional methods such as RNA interference. These cell lines provide a versatile platform that can be easily adapted for various assays, including functional assays, validation of drug leads, and mechanistic studies.

The value of NFIA Gene Knockout Cell Lines to researchers and clinicians cannot be overstated. They afford the opportunity to explore genetic contributions to disease in a controlled environment, leading to advancements in therapeutic approaches and the elucidation of complex biological interactions. Our company brings together advanced molecular biology techniques with a commitment to quality and support, ensuring that you have unrivaled tools for groundbreaking research. Trust NFIA Gene Knockout Cell Lines as an essential asset in your scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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