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NAA16 Knockout Cell Lines

Gene: NAA16

Official Full Name: N-alpha-acetyltransferase 16, NatA auxiliary subunitprovided by HGNC

Gene Summary: Enables ribosome binding activity. Involved in N-terminal protein amino acid acetylation; negative regulation of apoptotic process; and protein stabilization. Located in cytosol. Part of NatA complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15926 NAA16 Knockout cell line (HeLa) Human NAA16 1:3~1:6 Negative Online Inquiry
KO15927 NAA16 Knockout cell line (HCT 116) Human NAA16 1:2~1:4 Negative Online Inquiry
KO15928 NAA16 Knockout cell line (HEK293) Human NAA16 1:3~1:6 Negative Online Inquiry
KO15929 NAA16 Knockout cell line (A549) Human NAA16 1:3~1:4 Negative Online Inquiry

Background

NAA16 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to study the function of the NAA16 gene, which encodes an essential enzyme involved in protein N-terminal acetylation. These cell lines have been created using CRISPR/Cas9 technology to facilitate precise disruption of the NAA16 gene, allowing researchers to assess the biological consequences of its absence on cellular processes. Employing these knockouts, scientists can elucidate pathways critical to cellular growth, differentiation, and response to stress, thus providing essential insights into both normal physiology and disease mechanisms.

The key function of these cell lines rests in their ability to mimic pathological conditions that may arise from NAA16 dysfunction. The knockout of this gene disrupts the acetylation of proteins, leading to downstream effects that researchers can quantitatively and qualitatively analyze. Understanding these mechanisms can drive new hypotheses in regards to cellular aging, cancer research, and metabolic disorders, making NAA16 Gene Knockout Cell Lines invaluable for translational research applications.

In clinical settings, these models contribute to the development of novel therapeutic strategies, targeting diseases that stem from improper protein modification. Compared to alternative models, which may utilize overexpression systems or non-targeted knockouts, the precision and specificity of NAA16 Gene Knockout Cell Lines allow for more accurate modeling of human pathophysiology, significantly improving experimental reproducibility and reliability of results.

These cell lines are not merely research tools; they embody our commitment to advancing scientific knowledge through innovative biotechnology products. With extensive expertise in genetic engineering and a robust pipeline of cellular models, our company remains dedicated to providing exceptional resources that support the cutting-edge research of today and tomorrow. Researchers and clinicians alike will find unique value in utilizing the NAA16 Gene Knockout Cell Lines, as they pave the way for scientific discovery and breakthroughs in multiple therapeutic areas.

Please note that all services are for research use only. Not intended for any clinical use.

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