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MYO6 Knockout Cell Lines

Gene: MYO6

Official Full Name: myosin VIprovided by HGNC

Gene Summary: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36465 MYO6 Knockout cell line (HeLa) Human MYO6 1:3~1:6 Negative Online Inquiry
KO36466 MYO6 Knockout cell line (HCT 116) Human MYO6 1:2~1:4 Negative Online Inquiry
KO36467 MYO6 Knockout cell line (HEK293) Human MYO6 1:3~1:6 Negative Online Inquiry
KO36468 MYO6 Knockout cell line (A549) Human MYO6 1:3~1:4 Negative Online Inquiry

Background

MYO6 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the MYO6 gene, which encodes for myosin VI, a motor protein involved in intracellular transport and various cellular processes. This knockout approach allows researchers to study the specific functions and pathways related to MYO6 and its role in cellular dynamics, including endocytosis, vesicle trafficking, and cellular motility. By utilizing CRISPR-Cas9 technology, these cell lines provide a precise and effective method to disrupt MYO6 gene function, enabling comprehensive investigation into its contributions to health and disease.

The key functionality of MYO6 Gene Knockout Cell Lines lies in their ability to mimic conditions associated with MYO6 dysfunction, such as certain neurological disorders, cancer, and other metabolic diseases. Through such models, researchers can elucidate the pathological mechanisms that stem from MYO6 deficiency, potentially unveiling novel therapeutic targets. These cell lines are invaluable in drug discovery efforts, where understanding the molecular underpinnings can lead to targeted interventions and innovative treatments.

Compared to existing alternatives, MYO6 Knockout Cell Lines are distinguished by their enhanced specificity and reliability, derived from rigorous validation and characterization. This precision allows for reproducible results in both basic and applied research, giving scientists an edge in their studies. Furthermore, the ease of use, coupled with the potential for high-throughput screening, makes these cell lines a preferred choice for laboratories focused on cellular and molecular biology.

For researchers and clinicians keen on advancing their studies in the realms of cell biology and therapeutic development, MYO6 Gene Knockout Cell Lines are a vital tool that bridges the gap between fundamental research and clinical applications. They enable a deeper understanding of MYO6-related mechanisms in a wide array of biological contexts. With a commitment to quality and innovation, our company emphasizes unparalleled support and expertise in providing high-caliber biological products that propel research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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