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MPV17 Knockout Cell Lines

Gene: MPV17

Official Full Name: mitochondrial inner membrane protein MPV17provided by HGNC

Gene Summary: This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS). [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36568 MPV17 Knockout cell line (HeLa) Human MPV17 1:3~1:6 Negative Online Inquiry
KO36569 MPV17 Knockout cell line (HCT 116) Human MPV17 1:2~1:4 Negative Online Inquiry
KO36570 MPV17 Knockout cell line (HEK293) Human MPV17 1:3~1:6 Negative Online Inquiry
KO36571 MPV17 Knockout cell line (A549) Human MPV17 1:3~1:4 Negative Online Inquiry

Background

MPV17 Gene Knockout Cell Lines are specialized cell lines engineered to lack the MPV17 gene, a critical component involved in mitochondrial function and cellular metabolism. These knockout models provide a unique platform for studying mitochondrial disorders, oxidative stress responses, and cellular energy metabolism. By eliminating the MPV17 gene, these cell lines mimic specific pathological conditions associated with mitochondrial dysfunction, allowing researchers to explore the underlying mechanisms and potential therapeutic interventions.

The primary functions of MPV17 are linked to the regulation of mitochondrial membrane integrity and the maintenance of cellular homeostasis. Gene knockout disrupts these processes, leading to alterations in ATP production, increased oxidative stress, and impaired energy metabolism. Researchers utilizing these cell lines can investigate how the absence of MPV17 contributes to various metabolic diseases, neurodegenerative disorders, and age-related conditions, thereby advancing our understanding of complex biological systems.

In both research and clinical settings, MPV17 Gene Knockout Cell Lines serve as valuable tools for drug discovery and toxicity testing, facilitating the identification of novel therapeutic compounds aimed at restoring mitochondrial function. Their application extends to providing insights into the pathophysiology of diseases related to energy metabolism, which is increasingly relevant given the rise in mitochondrial diseases and their associated health burdens.

Compared to alternative models, the specificity and precision of the MPV17 knockout cell lines present significant advantages. They offer a more accurate representation of mitochondrial dysfunction, thereby enhancing the predictive power of experimental results. Furthermore, these cell lines are readily adaptable for high-throughput screening and can be utilized in various assays, promoting versatility in research applications.

For researchers and clinicians committed to understanding mitochondrial biology and developing therapeutic strategies, MPV17 Gene Knockout Cell Lines represent an indispensable resource. By leveraging our expertise in cellular engineering and genetic manipulation, our company is dedicated to providing high-quality biological products that empower scientific discovery and innovation in the rapidly evolving field of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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