Gene: MB
Official Full Name: myoglobinprovided by HGNC
Gene Summary: This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric oxide. Multiple transcript variants encoding distinct isoforms exist for this gene. [provided by RefSeq, May 2020]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05986 | MB Knockout cell line (HeLa) | Human | MB | 1:3~1:6 | Negative | Online Inquiry |
KO05987 | MB Knockout cell line (A549) | Human | MB | 1:3~1:4 | Negative | Online Inquiry |
MB Gene Knockout Cell Lines are sophisticated cellular models developed to facilitate the study of gene function and the underlying mechanisms of various biological processes. These cell lines are engineered through targeted gene editing techniques, such as CRISPR-Cas9 or homology-directed repair, to disrupt the expression of specific genes. This results in a decisive knockout that allows researchers to observe the phenotypic consequences of gene loss, elucidating pathways critical for development, disease progression, and drug response.
The primary function of MB Gene Knockout Cell Lines lies in their ability to provide insight into gene function by enabling the study of gene product interactions, cellular signaling pathways, and metabolic processes. Researchers can employ these models to investigate the roles of key genes in physiological and pathological conditions, thus advancing the understanding of diseases such as cancer, neurodegeneration, and various genetic disorders. The knockout models can be employed in high-throughput screening applications, providing an efficient tool for drug discovery and development in a clinical setting.
A significant advantage of choosing MB Gene Knockout Cell Lines over alternative systems is their specificity and reproducibility. These cell lines are meticulously validated to ensure that the gene of interest has been effectively knocked out, thus reducing background variability that can mislead findings. Additionally, MB Gene Knockout Cell Lines are available in various biologically relevant backgrounds, offering an adaptable platform tailored for diverse experimental needs.
For researchers and clinicians alike, the value of MB Gene Knockout Cell Lines is substantial, as they not only enhance the understanding of gene function but also support the translation of basic research into therapeutic strategies. By enabling more accurate modeling of human diseases, these cell lines pave the way toward innovative treatment approaches.
With years of experience in the field of genomic technologies and a commitment to advancing biotechnology, our company specializes in providing high-quality biological products, including the MB Gene Knockout Cell Lines. Our dedication to excellence ensures that researchers have access to the tools necessary to further their scientific inquiries and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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