Gene: MARCHF6
Official Full Name: membrane associated ring-CH-type finger 6provided by HGNC
Gene Summary: This gene encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc finger motifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01961 | MARCHF6 Knockout cell line (HeLa) | Human | MARCHF6 | 1:3~1:6 | Negative | Online Inquiry |
KO01962 | MARCHF6 Knockout cell line (HCT 116) | Human | MARCHF6 | 1:2~1:4 | Negative | Online Inquiry |
KO01963 | MARCHF6 Knockout cell line (HEK293) | Human | MARCHF6 | 1:3~1:6 | Negative | Online Inquiry |
KO01964 | MARCHF6 Knockout cell line (A549) | Human | MARCHF6 | 1:3~1:4 | Negative | Online Inquiry |
MARCHF6 Gene Knockout Cell Lines are specialized cell lines engineered to lack the MARCHF6 gene, which encodes a membrane-associated RING-CH (MARCH) E3 ubiquitin ligase. This innovative product operates through the selective disruption of the MARCHF6 gene, thereby enabling researchers to study the gene's function and its role in various cellular pathways. These knockout cell lines facilitate the investigation of post-translational modifications, specifically ubiquitination, which influences protein degradation, stability, and signaling pathways.
The scientific importance of MARCHF6 Gene Knockout Cell Lines is underscored by their utility in research areas such as cancer biology, immunology, and neurobiology. By providing a system to elucidate the gene's involvement in cell proliferation, apoptosis, and immune response modulation, these cell lines serve as a critical tool for understanding disease mechanisms and developing therapeutic strategies. Furthermore, they can be employed in drug discovery and development, allowing scientists to assess the efficacy and safety of potential pharmaceutical agents in a controlled environment.
One of the key advantages of MARCHF6 Gene Knockout Cell Lines is their specificity and reliability. Unlike traditional knockdown approaches, which can result in off-target effects and variable gene silencing, our knockout cell lines provide a complete gene deletion, ensuring precise experimental conditions. This specificity enhances experimental reproducibility and confidence in the data, making these cell lines a superior choice for researchers seeking valid and robust results.
For researchers and clinicians, the ability to investigate the critical roles of the MARCHF6 gene in various contexts can yield significant insights that drive innovative therapies. Our company has extensive expertise in the development of genetically modified cell lines, ensuring high-quality products that meet the rigorous demands of modern scientific research. With a commitment to advancing biological products, we empower researchers with the tools they need to unlock the secrets of gene function and disease pathophysiology.
Please note that all services are for research use only. Not intended for any clinical use.
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