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MAP9 Knockout Cell Lines

Gene: MAP9

Official Full Name: microtubule associated protein 9provided by HGNC

Gene Summary: ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16339 MAP9 Knockout cell line (HEK293) Human MAP9 1:3~1:6 Negative Online Inquiry
KO16340 MAP9 Knockout cell line (A549) Human MAP9 1:3~1:4 Negative Online Inquiry

Background

MAP9 Gene Knockout Cell Lines are genetically modified cell lines designed to lack the MAP9 gene, which encodes a microtubule-associated protein playing a critical role in cellular processes such as mitosis and cell signaling. These knockout models allow for the precise study of the MAP9 gene's function and its implications in cellular behavior and disease mechanisms. By utilizing CRISPR-Cas9 technology, these cell lines exhibit a definitive deletion of MAP9, ensuring researchers can analyze the consequences of its absence in a controlled environment.

The key functions of MAP9 involve stabilizing microtubules during spindle assembly, which is vital for proper chromosome segregation. By studying these knockout cell lines, researchers can explore not only the direct effects on cellular division but also how alterations in microtubule dynamics may contribute to diseases such as cancer, where aberrant cell division is a hallmark. These models have extensive applications in both basic research and translational studies, providing insights into potential therapeutic targets and strategies to combat MAP9-related pathologies.

What sets MAP9 Gene Knockout Cell Lines apart from alternative models is the specificity and precision of CRISPR-mediated gene editing, which eliminates off-target effects and ensures reproducibility of results. This high specificity enhances the reliability of experimental outcomes, giving users confidence in their research findings. The convenience of working with established cell lines also allows for faster experimental timelines and streamlined workflows, making them ideal for high-throughput screening or drug discovery.

For researchers and clinicians focusing on microtubule dynamics, cancer biology, or genetic regulation, MAP9 Gene Knockout Cell Lines represent a valuable resource, enabling the dissection of complex biological questions and driving innovation in therapeutic development. Our company prides itself on delivering high-quality, rigorously validated cellular models designed to meet the needs of the scientific community, reflecting our commitment to advancing research through excellence in biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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