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MAP7 Knockout Cell Lines

Gene: MAP7

Official Full Name: microtubule associated protein 7provided by HGNC

Gene Summary: The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33626 MAP7 Knockout cell line (HeLa) Human MAP7 1:3~1:6 Negative Online Inquiry
KO33627 MAP7 Knockout cell line (HCT 116) Human MAP7 1:2~1:4 Negative Online Inquiry
KO33628 MAP7 Knockout cell line (HEK293) Human MAP7 1:3~1:6 Negative Online Inquiry
KO33629 MAP7 Knockout cell line (A549) Human MAP7 1:3~1:4 Negative Online Inquiry

Background

MAP7 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed for the study of the MAP7 gene's function. MAP7, or Microtubule-Associated Protein 7, is crucial in regulating microtubule dynamics and intracellular transport processes. The MAP7 Gene Knockout Cell Lines are developed using CRISPR-Cas9 technology, which allows for precise editing of the genome, enabling researchers to eliminate MAP7 expression. This loss of function can significantly aid in understanding the gene's role in various cellular processes, pathways, and its implications in health and disease.

The cellular mechanisms explored through these knockout cell lines can reveal vital insights into neurodegenerative disorders, cancer progression, and cellular signaling pathways. By studying the phenotypic changes resulting from MAP7 knockout, researchers can uncover mechanisms of microtubule stability and motility that are essential for cell division and signaling.

One of the key advantages of using MAP7 Gene Knockout Cell Lines is the high specificity and efficiency of the CRISPR-Cas9 method, which reduces off-target effects common in other gene-editing techniques. Additionally, these cell lines come with thorough validation, including confirmation of effective gene disruption and consistent performance across various assays, making them a reliable choice for experimental design.

For researchers and clinicians, the MAP7 Gene Knockout Cell Lines offer the unique opportunity to develop targeted therapies and diagnostic tools tailored to conditions influenced by MAP7 activity. The understanding garnered from these studies could lead to advancements in therapeutic strategies aimed at diseases characterized by microtubule dysfunction.

As a leader in providing high-quality biological research products, our company leverages a wealth of expertise to ensure that researchers have access to innovative tools like the MAP7 Gene Knockout Cell Lines, driving scientific discovery and potential clinical breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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