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LIPT2 Knockout Cell Lines

Gene: LIPT2

Official Full Name: lipoyl(octanoyl) transferase 2provided by HGNC

Gene Summary: This gene encodes a mitochondrial protein that catalyzes the transfer of octanoic acid to lipoate-dependent enzymes such as octanoyl-ACP. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16523 LIPT2 Knockout cell line (HeLa) Human LIPT2 1:3~1:6 Negative Online Inquiry
KO16524 LIPT2 Knockout cell line (HEK293) Human LIPT2 1:3~1:6 Negative Online Inquiry
KO16525 LIPT2 Knockout cell line (A549) Human LIPT2 1:3~1:4 Negative Online Inquiry

Background

LIPT2 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the investigation of the LIPT2 gene's function and its implications in various biological processes and diseases. The production of these cell lines employs advanced CRISPR-Cas9 technology, resulting in precise gene editing that disrupts the LIPT2 gene. This knockout capability allows researchers to elucidate the gene's role in lipid metabolism, cellular signaling, and potential associations with metabolic disorders.

The primary function of LIPT2 Gene Knockout Cell Lines lies in their unique ability to mimic pathological conditions by removing the influence of LIPT2, thus providing a controlled experimental environment to study resultant phenotypic changes. Through the knock-out mechanism, researchers can investigate metabolic pathways affected by LIPT2, identify downstream target genes, and assess cellular responses, including stress responses and altered lipid profiles.

These cell lines hold significant scientific importance and find applications in both research and clinical settings. In research, they serve as a critical tool for dissecting metabolic pathways and identifying potential therapeutic targets, especially in the context of obesity and type 2 diabetes. Clinically, understanding LIPT2 functions can pave the way for innovative treatment strategies and personalized medicine approaches aimed at metabolic diseases.

LIPT2 Gene Knockout Cell Lines offer several advantages over traditional models, such as greater accuracy in recapitulating genetic alterations, reduced off-target effects, and enhanced reproducibility. Unlike conventional cells that may express variable levels of the target gene, these knockout lines provide a consistent platform for rigorous experimentation, greatly simplifying comparative studies.

For researchers and clinicians alike, the ability to study the absence of LIPT2 provides invaluable insights into its biological role and potential therapeutic implications. The availability of these knockout cell lines significantly accelerates research timelines and increases experimental efficiency.

At our company, we specialize in providing high-quality genetic models designed for cutting-edge research. With our expertise in biotechnological advancements, we ensure that our LIPT2 Gene Knockout Cell Lines meet the rigorous standards required for effective scientific inquiry and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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