Home / LARP4 Knockout Cell Lines

LARP4 Knockout Cell Lines

Gene: LARP4

Official Full Name: La ribonucleoprotein 4provided by HGNC

Gene Summary: Enables mRNA 3'-UTR binding activity and poly(A) binding activity. Involved in cytoskeleton organization; positive regulation of translation; and regulation of cell morphogenesis. Located in cytoplasmic stress granule and cytosolic small ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00913 LARP4 Knockout cell line(HEK293) Human LARP4 1:3~1:6 Negative Online Inquiry
KO16596 LARP4 Knockout cell line (HeLa) Human LARP4 1:3~1:6 Negative Online Inquiry
KO16597 LARP4 Knockout cell line (HCT 116) Human LARP4 1:2~1:4 Negative Online Inquiry
KO16598 LARP4 Knockout cell line (A549) Human LARP4 1:3~1:4 Negative Online Inquiry

Background

LARP4 Gene Knockout Cell Lines are specialized, genetically engineered cell lines developed to facilitate the study of the LARP4 gene and its biological functions. The LARP4 protein is known to be involved in the regulation of gene expression and plays a significant role in cellular responses to stress. By employing the CRISPR-Cas9 gene-editing technology, our LARP4 knockout cell lines completely disrupt the expression of the LARP4 gene, thereby providing a precise and effective tool for researchers investigating the physiological roles of this protein in various biological processes.

The key mechanism by which these knockout cell lines operate hinges on the introduction of dual guide RNAs that specifically target the LARP4 gene, causing mutations that prevent transcription. This results in a loss of LARP4 function, allowing for the examination of downstream effects on cell proliferation, differentiation, and response to environmental stressors. Such studies are crucial for elucidating the pathways in which LARP4 is involved, particularly in cancer biology and cellular homeostasis.

The scientific importance of these cell lines is underscored by their diverse applications, ranging from basic research to more translational studies exploring potential therapeutic targets. They provide valuable insights into the regulatory mechanisms of gene expression and can assist in understanding disease mechanisms associated with aberrant LARP4 activity.

One of the distinct advantages of our LARP4 Gene Knockout Cell Lines is the thorough validation of each line for knockout efficiency and phenotype stability, which are often lacking in alternative models. This meticulous attention to detail reduces variability in experimental outcomes and assures quality, making them particularly attractive to researchers looking to conduct replicable studies.

For researchers and clinicians alike, the value of our LARP4 Gene Knockout Cell Lines lies in their ability to provide a consistent and reliable platform for investigating key biological processes, ultimately leading to advancements in disease understanding and treatment strategies. Our expertise in genetic engineering and commitment to high-quality biological products positions us as a trusted partner in your research endeavors, ensuring that you have access to the best tools to facilitate your scientific investigations.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.