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LAPTM4A Knockout Cell Lines

Gene: LAPTM4A

Official Full Name: lysosomal protein transmembrane 4 alphaprovided by HGNC

Gene Summary: This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00328 LAPTM4A Knockout cell line (HeLa) Human LAPTM4A 1:3~1:6 Negative Online Inquiry
KO02369 LAPTM4A Knockout cell line (HCT 116) Human LAPTM4A 1:2~1:4 Negative Online Inquiry
KO02370 LAPTM4A Knockout cell line (HEK293) Human LAPTM4A 1:3~1:6 Negative Online Inquiry
KO02371 LAPTM4A Knockout cell line (A549) Human LAPTM4A 1:3~1:4 Negative Online Inquiry

Background

LAPTM4A Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the functions and pathways associated with the lysosomal associated protein transmembrane 4 alpha (LAPTM4A) gene. These knockout cell lines have been created using CRISPR/Cas9 technology to remove the LAPTM4A gene, allowing for the investigation of its role in cellular processes such as endocytosis, lysosomal function, and cellular signaling pathways.

The primary function of LAPTM4A is believed to involve the regulation of protein trafficking and lysosomal degradation, which has significant implications in the maintenance of cellular homeostasis. By utilizing LAPTM4A knockout cell lines, researchers can gain insights into how the absence of this gene affects cellular functions and contributes to disease states such as cancer or neurodegeneration.

The scientific importance of this product is underscored by its applications in various research areas, including cancer biology, neurobiology, and apoptosis studies. LAPTM4A has been implicated in tumor progression and the modulation of immune responses, making these cell lines invaluable for researchers investigating novel therapeutic targets or biomarkers. Clinicians may also benefit from this product as it aids in the identification of potential interventions for conditions linked to lysosomal dysfunction.

What sets LAPTM4A Gene Knockout Cell Lines apart from conventional cell lines is their specific genetic alteration, allowing for precise and targeted studies. Unlike standard models that may express the LAPTM4A gene, these knockout lines provide a unique platform to explore gene function without the confounding influence of normal gene expression. This enhanced specificity facilitates more robust conclusions in experimental settings.

For researchers and clinicians alike, the ability to manipulate LAPTM4A functions with ease opens up avenues for innovative research and therapeutic development, making these cell lines a vital asset in the scientific toolkit. Our company specializes in providing high-quality, rigorously validated biological products, ensuring that researchers have reliable tools essential for advancing their studies and contributing to the broader scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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