Gene: LAD1
Official Full Name: ladinin 1provided by HGNC
Gene Summary: The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36853 | LAD1 Knockout cell line (HCT 116) | Human | LAD1 | 1:2~1:4 | Negative | Online Inquiry |
LAD1 Gene Knockout Cell Lines are engineered human cellular models specifically designed to assess the biological functions of the LAD1 gene. These cell lines are created using CRISPR-Cas9 gene-editing technology to disrupt the normal expression of the LAD1 gene, enabling researchers to investigate the downstream effects of its loss. By completely inactivating the gene, these knockout cell lines serve as essential tools for elucidating the role of LAD1 in various physiological and pathological processes, particularly those related to immune response and cellular adhesion dynamics.
The key function of LAD1 is hypothesized to be involved in cellular adherence and motility, with implications for understanding cell signaling pathways that regulate these processes. By utilizing LAD1 Gene Knockout Cell Lines, researchers can examine alterations in adhesion properties, migration patterns, and signal transduction, providing insights into disorders characterized by aberrant cell adhesion, such as autoimmune diseases and cancer metastasis.
In both research and clinical settings, the scientific importance of LAD1 Gene Knockout Cell Lines is underscored by their versatility in drug response testing and translational research. They facilitate high-throughput screening for compounds targeting LAD1-related pathways and contribute to biomarker discovery, which is crucial for the development of targeted therapies.
Compared to traditional cell lines, which may express functional LAD1 protein, our LAD1 Gene Knockout Cell Lines offer a unique advantage by providing a clear phenotype devoid of LAD1 activity. This specificity enhances the precision of investigations into LAD1's role, making data interpretations more reliable and reproducible.
This product is invaluable for researchers, clinicians, and pharmaceutical developers who aim to deepen their understanding of LAD1's contributions to human health. By deploying these knockout cell lines in their studies, users can advance their research with confidence that their findings will add to the growing body of knowledge surrounding LAD1 function.
Our company stands at the forefront of genetic engineering solutions, providing high-quality biological products that empower researchers and clinicians in their quest for scientific breakthroughs. With a commitment to excellence and innovation, we continuously strive to enhance the quality and utility of our offerings, including our expertly crafted LAD1 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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