Gene: KRBOX4
Official Full Name: KRAB box domain containing 4provided by HGNC
Gene Summary: This encodes a zinc finger protein with an N-terminal KRAB (Kruppel-associated) domain found in transcriptional repressors. This gene is located in a region of the X chromosome thought to be involved in nonsyndromic X-linked cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16635 | KRBOX4 Knockout cell line (HeLa) | Human | KRBOX4 | 1:3~1:6 | Negative | Online Inquiry |
KO16636 | KRBOX4 Knockout cell line (HCT 116) | Human | KRBOX4 | 1:2~1:4 | Negative | Online Inquiry |
KO16637 | KRBOX4 Knockout cell line (HEK293) | Human | KRBOX4 | 1:3~1:6 | Negative | Online Inquiry |
KO16638 | KRBOX4 Knockout cell line (A549) | Human | KRBOX4 | 1:3~1:4 | Negative | Online Inquiry |
KRBOX4 Gene Knockout Cell Lines are advanced cellular models that have been genetically engineered to disrupt the expression of the KRBOX4 gene, a crucial component in various biological pathways involving cell growth, differentiation, and susceptibility to diseases. These knockout cell lines are derived using technologies such as CRISPR-Cas9 or RNA interference, ensuring a precise and efficient ablation of the target gene. The mechanism underlying their functionality is based on eliminating the KRBOX4 gene, allowing researchers to investigate the resultant phenotypic and molecular changes, thereby elucidating the gene's role in cellular contexts.
The scientific importance of KRBOX4 Gene Knockout Cell Lines lies in their utility for various applications in both fundamental research and therapeutic development. They provide invaluable tools for studying gene function, exploring potential drug targets, and modeling diseases. In clinical research settings, they can be employed to assess the effects of pharmacological compounds on KRBOX4-related pathways, facilitating the identification of novel therapeutic strategies for diseases linked to aberrant KRBOX4 signaling, such as certain cancers or metabolic disorders.
One of the distinctive advantages of KRBOX4 Gene Knockout Cell Lines is the precision and reliability offered by the knockout technology. Unlike traditional knockout methods, which often result in off-target effects, our cell lines are crafted with minimal unintended genetic alterations, providing researchers with confidence in their experimental results. Furthermore, our product comes with comprehensive characterization data, which includes functional assays that demonstrate the complete ablation of KRBOX4 activity.
Researchers and clinicians can greatly benefit from these cell lines, as they enable the comprehensive study of the KRBOX4 gene's implications in various biological processes, rendering them essential for those aiming to develop targeted therapies or elucidate mechanisms of disease. Moreover, our commitment to quality and precision at [Your Company Name] underlines our expertise in creating cutting-edge biological products that support the research community in unveiling the intricacies of gene function. By choosing KRBOX4 Gene Knockout Cell Lines, researchers are equipping themselves with a powerful tool to advance scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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