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JCAD Knockout Cell Lines

Gene: JCAD

Official Full Name: junctional cadherin 5 associatedprovided by HGNC

Gene Summary: This gene encodes an endothelial cell-to-cell junction protein. Naturally occurring mutations in this gene are associated with coronary artery disease, late onset alzheimer disease, and emphysema distribution. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16858 JCAD Knockout cell line (HCT 116) Human JCAD 1:2~1:4 Negative Online Inquiry
KO16859 JCAD Knockout cell line (HEK293) Human JCAD 1:3~1:6 Negative Online Inquiry
KO16860 JCAD Knockout cell line (A549) Human JCAD 1:3~1:4 Negative Online Inquiry

Background

JCAD Gene Knockout Cell Lines are specifically engineered cellular systems designed to facilitate the study of the JCAD gene’s role in various biological processes. These modified cell lines are created using state-of-the-art CRISPR/Cas9 gene-editing technology, which allows for precise and efficient disruption of the JCAD gene, promoting an in-depth analysis of its function and mechanism. The knockout of this gene enables researchers to investigate its involvement in critical cellular pathways, adhesion processes, and signaling events that contribute to different diseases, including cancer and cardiovascular disorders.

The key functions of JCAD Gene Knockout Cell Lines revolve around their ability to serve as versatile tools in both basic and applied research. Notably, these cell lines allow scientists to observe changes in cell morphology, adhesion, migration, and proliferation in the absence of the JCAD protein. This facilitates a more comprehensive understanding of how JCAD alters cellular responses under physiological and pathological conditions, thereby contributing to advancements in therapeutic strategies.

Scientifically, the importance of JCAD Gene Knockout Cell Lines cannot be overstated, as they provide a unique platform for the investigation of gene function in a controlled environment. In clinical settings, they have the potential to aid in the development of targeted therapies by identifying crucial cellular responses that can be manipulated for treatment purposes. Their use in drug screening and molecular assays makes them a valuable asset for both academic and pharmaceutical research.

Compared to alternative methods, JCAD Gene Knockout Cell Lines stand out due to their high specificity and efficiency in gene disruption, reduced off-target effects, and compatibility with a wide range of experimental setups. Unlike transient knockdown methods, these stable knockout lines ensure durable gene silencing, thereby providing consistent results across multiple experimental runs, which is essential for reproducibility in scientific research.

For researchers and clinicians focused on gene function and its therapeutic implications, JCAD Gene Knockout Cell Lines offer priceless insights and experimental reliability. Our company is committed to advancing scientific knowledge and innovation, backed by expertise in genetic engineering and cellular biology. We provide high-quality products that empower the scientific community to unlock new possibilities in understanding diseases and developing groundbreaking treatments.

Please note that all services are for research use only. Not intended for any clinical use.

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