Gene: INAVA
Official Full Name: innate immunity activatorprovided by HGNC
Gene Summary: Involved in several processes, including nucleotide-binding activity oligomerization domain containing 2 signaling pathway; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Located in cytoplasm and nuclear body. Implicated in inflammatory bowel disease 29. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16936 | INAVA Knockout cell line (HeLa) | Human | INAVA | 1:3~1:6 | Negative | Online Inquiry |
KO16937 | INAVA Knockout cell line (HCT 116) | Human | INAVA | 1:2~1:4 | Negative | Online Inquiry |
KO16938 | INAVA Knockout cell line (HEK293) | Human | INAVA | 1:3~1:6 | Negative | Online Inquiry |
KO16939 | INAVA Knockout cell line (A549) | Human | INAVA | 1:3~1:4 | Negative | Online Inquiry |
INAVA Gene Knockout Cell Lines are sophisticated biological tools designed to enable researchers to investigate gene function through targeted gene disruption. These cell lines are crafted using advanced CRISPR-Cas9 technology, which allows for precise deletion of specific genes, thus facilitating the study of their roles in various biological processes, disease mechanisms, and drug responses.
The key function of these knockout cell lines lies in their ability to model gene loss in a controlled environment. Upon the introduction of CRISPR-Cas9 components, the targeted gene is effectively rendered nonfunctional, enabling researchers to observe phenotypic changes that result from the gene's absence. This mechanism not only assists in elucidating gene functions but also aids in the identification of potential therapeutic targets and biomarkers.
The scientific importance of INAVA Gene Knockout Cell Lines is profound, particularly in the realms of genetic research, pharmacogenomics, and cancer biology. In clinical settings, these models are instrumental in the development of personalized medicine strategies, as they provide insights into how specific genetic alterations can impact disease progression and treatment efficacy. Furthermore, their use in high-throughput screening allows for rapid evaluation of gene-targeted therapies and novel drug compounds.
Compared to alternative models like traditional knockout mice, INAVA Gene Knockout Cell Lines offer distinct advantages, including lower costs, shorter generation times, and the ability to easily manipulate multiple genes concurrently. Their robustness ensures reproducibility and consistent results, essential for high-quality scientific research.
The inherent value of INAVA Gene Knockout Cell Lines for researchers and clinicians is undeniable, providing a versatile platform for investigating complex biological questions with significant translational impact. By utilizing these tools, scientists can draw closer to understanding the intricacies of gene function and its implications in human health and disease.
INAVA is committed to advancing biological research with precision-engineered solutions like our Gene Knockout Cell Lines, leveraging our expertise in genetic engineering to support the scientific community in its quest for discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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