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HEG1 Knockout Cell Lines

Gene: HEG1

Official Full Name: heart development protein with EGF like domains 1provided by HGNC

Gene Summary: Predicted to enable calcium ion binding activity. Involved in several processes, including negative regulation of Rho protein signal transduction; negative regulation of Rho-dependent protein serine/threonine kinase activity; and negative regulation of membrane permeability. Located in cell-cell junction. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02439 HEG1 Knockout cell line (HeLa) Human HEG1 1:3~1:6 Negative Online Inquiry
KO02440 HEG1 Knockout cell line (HCT 116) Human HEG1 1:2~1:4 Negative Online Inquiry
KO02441 HEG1 Knockout cell line (HEK293) Human HEG1 1:3~1:6 Negative Online Inquiry
KO02442 HEG1 Knockout cell line (A549) Human HEG1 1:3~1:4 Negative Online Inquiry

Background

HEG1 Gene Knockout Cell Lines are genetically modified cell lines in which the HEG1 gene has been effectively disrupted, enabling researchers to study the biological roles of this gene in cellular processes. The HEG1 protein is implicated in various signaling pathways that regulate cell adhesion, migration, and communication. By knocking out this gene, scientists can elucidate its specific contributions to these processes, thereby advancing our understanding of cellular biology and disease mechanisms.

The key function of HEG1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for in-depth functional studies. During experiments, researchers can assess changes in cellular behavior and signaling cascades activated in response to the absence of the HEG1 gene. This mechanistic insight can lead to the identification of potential therapeutic targets, particularly in disease models where aberrations in cell signaling are involved.

The scientific importance of HEG1 Gene Knockout Cell Lines extends into both research and clinical applications. In the research domain, these cell lines serve as essential tools for investigating the role of HEG1 in cancer metastasis, wound healing, and immune responses. Clinically, understanding the function of HEG1 could pave the way for novel therapeutic strategies for conditions like cancer and fibrotic diseases, where cell migration plays a pivotal role.

Compared to conventional cell lines, HEG1 Gene Knockout Cell Lines offer significant advantages, such as specificity in gene function analysis and a reduction in off-target effects that can confound results. Their unique selling point lies in their precise genetic modification, which allows for reproducibility and reliability in experimental setups, making them invaluable for researchers focused on mechanistic studies.

By integrating HEG1 Gene Knockout Cell Lines into research protocols, scientists and clinicians can enhance the efficiency of their investigations and improve the translational potential of their findings. Our company, dedicated to advancing genetic engineering solutions, provides high-quality, validated HEG1 Gene Knockout Cell Lines that are a testament to our commitment to scientific excellence and innovation in the field of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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