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GPR156 Knockout Cell Lines

Gene: GPR156

Official Full Name: G protein-coupled receptor 156provided by HGNC

Gene Summary: G protein-coupled receptors (GPCRs) are a large superfamily of cell surface receptors characterized by 7 helical transmembrane domains, together with N-terminal extracellular and C-terminal intracellular domains.[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17288 GPR156 Knockout cell line (HeLa) Human GPR156 1:3~1:6 Negative Online Inquiry

Background

GPR156 Gene Knockout Cell Lines are genetically engineered cell lines specifically created to lack the expression of the GPR156 gene, which encodes a G protein-coupled receptor implicated in a variety of physiological processes. These knockout cell lines serve as invaluable tools for researchers investigating the role of GPR156 in signal transduction pathways, cellular responses, and potential disease mechanisms. By providing a controlled environment devoid of GPR156 expression, scientists can study the receptor's function in a more definitive manner, elucidating its contributions to neurobiology, developmental processes, and possible links to disorders, including neurodegenerative diseases.

The key mechanism of these cell lines involves the specific knockout of the GPR156 gene using CRISPR-Cas9 technology or similar gene-editing methodologies, ensuring that downstream signaling pathways can be accurately assessed. Researchers can utilize these cells to dissect the cellular responses in the absence of GPR156, allowing for the identification of redundant pathways and compensatory mechanisms that may be activated in its absence.

The scientific importance of GPR156 knockout cell lines lies in their application across various fields of research, including pharmacology, toxicology, and molecular biology. By exploring the implications of GPR156 inhibition or loss, clinicians and researchers gain insights into potential therapeutic targets for a wide range of conditions characterized by altered receptor activity.

What sets our GPR156 Gene Knockout Cell Lines apart from alternatives is their robustness, reproducibility, and the extensive characterization data that accompanies them. Unlike other platforms, our knockout lines are subjected to rigorous validation processes, ensuring specificity and functionality, which significantly offsets variability common with less established cell lines.

For researchers and clinicians, opting for GPR156 Gene Knockout Cell Lines ensures access to a reliable, well-characterized resource that can significantly enhance their experimental outcomes. They represent a crucial asset in advancing our understanding of GPR156-related pathways and potential therapeutic interventions.

Our company prides itself on its commitment to providing high-quality biological products, underpinned by years of expertise in genetic engineering and cell line development. We aim to empower scientific discovery with tools that support innovation across the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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