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GPR135 Knockout Cell Lines

Gene: GPR135

Official Full Name: G protein-coupled receptor 135provided by HGNC

Gene Summary: Enables arrestin family protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in endosome and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17299 GPR135 Knockout cell line (HeLa) Human GPR135 1:3~1:6 Negative Online Inquiry
KO17300 GPR135 Knockout cell line (HCT 116) Human GPR135 1:2~1:4 Negative Online Inquiry
KO17301 GPR135 Knockout cell line (A549) Human GPR135 1:3~1:4 Negative Online Inquiry

Background

GPR135 Gene Knockout Cell Lines are precision-engineered cellular models designed to study the functional consequences of GPR135 gene disruption in various biological contexts. These cell lines have been created using advanced CRISPR/Cas9 gene-editing technology, enabling the targeted deletion of the GPR135 gene, a member of the G-protein coupled receptor family known to be involved in vital cellular signaling pathways.

The primary function of these knockout cell lines is to facilitate the exploration of the GPR135 receptor's role in physiological processes and pathologies, including cancer, neuroregenerative diseases, and metabolic disorders. By eliminating GPR135 expression, researchers can dissect the receptor's contribution to cell behavior, signaling cascades, and interaction networks, thereby unveiling potential therapeutic targets and disease mechanisms.

The scientific importance of GPR135 knockout cell lines lies in their application in both fundamental research and clinical settings. They serve as crucial tools for screening novel drugs, validating targets for new therapeutics, and elucidating the complex interplay of receptors in disease states. Furthermore, these cell lines can be utilized in high-throughput assays, allowing researchers to efficiently evaluate the effects of compounds or genetic modifications on cellular functions.

What sets our GPR135 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility. Manufactured under stringent quality control conditions, these cell lines exhibit consistent knockout efficiency and stability across passages. Additionally, our comprehensive customer support ensures that researchers maximize the utility of these models in their experimental designs.

In an era where precision medicine is becoming increasingly vital, GPR135 Gene Knockout Cell Lines offer unparalleled insights and stand as essential resources for researchers and clinicians aiming to unravel the complexities of cellular signaling. Our company has a proven track record of developing high-quality biological products that empower scientific innovation, reinforcing our commitment to advancing research in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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