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FUBP3 Knockout Cell Lines

Gene: FUBP3

Official Full Name: far upstream element binding protein 3provided by HGNC

Gene Summary: Enables single-stranded DNA binding activity. Involved in DNA-templated transcription; positive regulation of DNA-templated transcription; and positive regulation of gene expression. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33714 FUBP3 Knockout cell line (HeLa) Human FUBP3 1:3~1:6 Negative Online Inquiry
KO33715 FUBP3 Knockout cell line (HCT 116) Human FUBP3 1:2~1:4 Negative Online Inquiry
KO33716 FUBP3 Knockout cell line (HEK293) Human FUBP3 1:3~1:6 Negative Online Inquiry
KO33717 FUBP3 Knockout cell line (A549) Human FUBP3 1:3~1:4 Negative Online Inquiry

Background

FUBP3 Gene Knockout Cell Lines are a cutting-edge research tool designed to facilitate the study of the FUBP3 gene's role in cellular processes and diseases. These cell lines are engineered through CRISPR/Cas9 or similar gene-editing technologies to effectively disrupt the FUBP3 gene's expression, enabling scientists to investigate the fundamental biological functions associated with this key regulator of gene expression and cellular signaling pathways.

The primary mechanism of action of the FUBP3 knockout cell lines involves the alteration of the mRNA binding dynamics, thereby impacting downstream transcriptional activity. By providing a model in which FUBP3 is non-functional, researchers can conduct experiments to unveil its influence on cell proliferation, apoptosis, and response to stressors such as hypoxia or chemotherapy. This opens a gateway to understanding not only normal cellular physiology but also the pathological mechanisms underpinning diseases like cancer, where FUBP3 has been implicated.

In the realm of scientific research, the FUBP3 Gene Knockout Cell Lines hold critical importance for their applications in pharmacogenomics, cancer biology, and therapeutic development. They allow for high-throughput screening of potential therapeutic agents targeting FUBP3-associated pathways, thereby expediting drug discovery efforts and offering insights into personalized medicine approaches.

Compared to traditional gene silencing techniques like RNA interference, the knockout methodology offers a more enduring and complete abrogation of gene function, allowing for more definitive conclusions about gene roles. This feature enhances the specificity and robustness of experimental results, making the FUBP3 knockout cell lines an invaluable addition to any research laboratory.

For researchers and clinicians invested in understanding the complexities of gene regulation and disease mechanisms, the FUBP3 Gene Knockout Cell Lines are a unique and powerful tool that can lead to significant discoveries and advancements in therapeutic interventions. Our company prides itself on its dedication to innovation in biological products, backed by a team of experts with extensive experience in genetic engineering and molecular biology, ensuring that we offer only the highest quality tools for scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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