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ELF1 Knockout Cell Lines

Gene: ELF1

Official Full Name: E74 like ETS transcription factor 1provided by HGNC

Gene Summary: This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38060 ELF1 Knockout cell line (HeLa) Human ELF1 1:3~1:6 Negative Online Inquiry
KO38061 ELF1 Knockout cell line (HCT 116) Human ELF1 1:2~1:4 Negative Online Inquiry
KO38062 ELF1 Knockout cell line (HEK293) Human ELF1 1:3~1:6 Negative Online Inquiry
KO38063 ELF1 Knockout cell line (A549) Human ELF1 1:3~1:4 Negative Online Inquiry

Background

ELF1 Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate the study of the ELF1 gene, known for its critical role in regulating gene expression associated with immune response and cell differentiation. This product offers novel insights into ELF1’s function through the complete disruption of its coding sequence, enabling researchers to observe phenotypic changes and regulatory pathways that may otherwise be masked by functional redundancy in native systems.

The key mechanism of the ELF1 Gene Knockout Cell Lines lies in their precise genetic modifications, achieved through advanced CRISPR-Cas9 technology. This method ensures a highly efficient and specific elimination of ELF1, enabling detailed studies on its influence in various biological processes, such as T-cell development and function. Researchers utilizing these cell lines can investigate ELF1’s contributions to diseases such as autoimmune disorders and cancer, thus opening avenues for targeted therapeutic developments.

In both research and clinical settings, the importance of ELF1 Gene Knockout Cell Lines cannot be overstated. They permit the dissection of molecular pathways and provide a platform for high-throughput screening of therapeutic agents aimed at modulating ELF1-related pathways. Furthermore, such cell lines are invaluable for assessing drug efficacy and toxicity in a controlled, reproducible environment.

ELF1 Gene Knockout Cell Lines present significant advantages over traditional models, which often lack precision and may not adequately reflect human biology. Their superior specificity minimizes off-target effects and bolsters the reliability of experimental data. Given the drastic implications of modulating ELF1 activity, this product serves as a vital tool for researchers striving to provide innovative solutions in health care.

Our company is committed to delivering high-quality biological products founded on rigorous scientific research and excellence. With years of expertise in molecular biology and genetic engineering, we provide researchers and clinicians not only with state-of-the-art cell lines but also with unparalleled support to advance their research goals.

Please note that all services are for research use only. Not intended for any clinical use.

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